Association between adherence to the Dietary Approaches to Stop Hypertension diet and serum uric acid

作者全名："Feng, Jie; Huang, Yuchai; Wang, Haozhuo; Wang, Chao; Xu, Hongbin; Ke, Pan; He, Yan; Tian, Qingfeng; Cao, Shiyi; Lu, Zuxun"

作者地址："[Feng, Jie; Xu, Hongbin; Ke, Pan; Cao, Shiyi; Lu, Zuxun] Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Dept Social Med & Hlth Management, Wuhan, Peoples R China; [Huang, Yuchai] Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Hlth Management Ctr, Wuhan, Hubei, Peoples R China; [Wang, Haozhuo] Chongqing Med Univ, Sch Publ Hlth & Management, Chongqing, Peoples R China; [Wang, Chao] Wuhan Univ, Sch Publ Hlth, Wuhan, Hubei, Peoples R China; [He, Yan; Tian, Qingfeng] Zhengzhou Univ, Sch Publ Hlth, Zhengzhou, Henan, Peoples R China"

通信作者："Cao, SY; Lu, ZX (通讯作者)，Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Dept Social Med & Hlth Management, Wuhan, Peoples R China."

来源：SCIENTIFIC REPORTS

ESI学科分类：Multidisciplinary

WOS号：WOS:000985360700064

JCR分区：Q1

影响因子：3.8

年份：2023

卷号：13

期号：1

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结束页：　

文献类型：Article

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摘要："To explore the relationship between Dietary Approaches to Stop Hypertension (DASH) diet and serum uric acid (SUA) levels among the Chinese adult population, and verify the mediating effect of BMI between DASH diet and SUA levels. A total of 1125 adults were investigated using a self-administered food frequency questionnaire. SUA levels were determined by uricase colorimetry. The total DASH score ranged from 9 to 72. The relationship between the DASH diet and SUA levels was examined by multiple adjusted regression analysis. Method of Bootstrap was used to test the mediation effect of BMI in the correlation of the DASH diet and SUA levels. After multivariable adjustment, there was a significant linear relationship between the DASH diet and SUA (P < 0.001). Compared with the lowest group, SUA of participants in group of highest DASH diet score decreased by 34.907 (95% CI - 52.227, - 17.588; P trend < 0.001) mu mol/L. The association between the DASH diet scores and SUA levels was partly mediated by BMI (- 0.26, Bootstrap 95% CI - 0.49, - 0.07), with 10.53% of the total effect being mediated. Adopting the DASH diet might be helpful in reducing SUA level, and the effect might be partly mediated by BMI."

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