The sclerosing sertoli cell tumor of the testis: a case report

作者全名："Tang, Xueyao; Hu, Yifan; Zhou, Hong; Zhou, Yang"

作者地址："[Tang, Xueyao; Zhou, Hong; Zhou, Yang] Chongqing Med Univ, Southwest Jiao Tong Univ, Peoples Hosp Chengdu 3, Dept Ultrasound,Affiliated Chengdu Hosp 2,Clin Col, Chengdu, Sichuan, Peoples R China; [Hu, Yifan] Chongqing Med Univ, Southwest Jiao Tong Univ, Peoples Hosp Chengdu 3, Dept Pathol,Affiliated Chengdu Hosp 2,Clin Coll, Chengdu, Sichuan, Peoples R China"

通信作者："Zhou, Y (通讯作者)，Chongqing Med Univ, Southwest Jiao Tong Univ, Peoples Hosp Chengdu 3, Dept Ultrasound,Affiliated Chengdu Hosp 2,Clin Col, Chengdu, Sichuan, Peoples R China."

来源：DIAGNOSTIC PATHOLOGY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000987156100001

JCR分区：Q2

影响因子：2.4

年份：2023

卷号：18

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Sclerosing sertoli cell tumor; Sertoli cell tumor; Testicular neoplasm; Case report

摘要："BackgroundTesticular Sertoli cell tumor (SCT) is very rare sex cord-gonadal stromal tumor, and sclerosing SCT (SSCT) is even rarer. So far, no more than 50 cases of SSCT have been reported. 80% of SSCTs are less than 2 cm in diameter, large volume mass is pretty unusual. SSCT is usually benign with very low malignant potential. However, it is easily misdiagnosed as a malignant tumor resulting in the removal of the entire testicle.Case presentationA 55-year-old Chinese male patient presented with a six months' history of right testis progressively enlargement and negative tumor markers. The physical examination was nothing special except for swelling in the right testicle. Imaging identified a large mass in right testicle with rich blood. A right radical orchiectomy was performed on suspicion of malignancy. However, the tumor was postoperatively diagnosed as SSCT, which pathologically consisted of a tubular pattern with regular nuclei and embedded in a densely collagenous stroma, as well as diffusely positive for vimentin, beta-catenin and synaptophysin. After 7 months of follow up, no evidence of local recurrence and metastasis has been observed.ConclusionThis rare case is helpful to expand the knowledge of the testicular tumor and alert us fully understand the rare variant of SCTs in order to choose the optimal management when they encounter SSCT."

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