Obstructive sleep apnea affects the psychological and behavioural development of children-a case-control study

作者全名："Hai, Yang; Kou, Wei; Gu, Zheng; Zhang, Cheng; Zou, Qiyuan; Wang, Fan; Yao, Hongbing; Wei, Ping"

作者地址："[Hai, Yang; Kou, Wei; Gu, Zheng; Zhang, Cheng; Zou, Qiyuan; Wang, Fan; Yao, Hongbing; Wei, Ping] Childrens Hosp Chongqing Med Univ, Natl Clin Res Ctr Child Hlth & Disorders, Minist Educ Key Lab Child Dev & Disorders, Dept Otolaryngol,Chongqing Key Lab Translat Med Re, Chongqing, Peoples R China; [Hai, Yang] Chongqing Youyou Baobei Women & Childrens Hosp, Dept Otolaryngol, Chongqing, Peoples R China"

通信作者："Wei, P (通讯作者)，Childrens Hosp Chongqing Med Univ, Natl Clin Res Ctr Child Hlth & Disorders, Minist Educ Key Lab Child Dev & Disorders, Dept Otolaryngol,Chongqing Key Lab Translat Med Re, Chongqing, Peoples R China."

来源：JOURNAL OF SLEEP RESEARCH

ESI学科分类：NEUROSCIENCE & BEHAVIOR

WOS号：WOS:000988378300001

JCR分区：Q2

影响因子：3.4

年份：2023

卷号：　

期号：　

开始页：　

结束页：　

文献类型：Article; Early Access

关键词：anxiety; autism symptoms; depression; obstructive sleep apnea; paediatric psychological and behavioural development

摘要："This study aims to investigate the effects of obstructive sleep apnea on paediatric psychological and behavioural abnormalities. A total of 1086 paediatric patients with obstructive sleep apnea and 728 sample snoring controls were enrolled in the study. Patients with obstructive sleep apnea underwent bilateral tonsillectomy plus adenoidectomy or adenoidectomy alone. Repeated Autism Behaviour Checklist, Spence Children's Anxiety Scale, and Children's Depression Inventory were performed to assess the autism symptoms, anxiety level and depressive symptoms before and after surgery. The score of Autism Behaviour Checklist in preschool children with obstructive sleep apnea was higher than that in control. In school children with obstructive sleep apnea, the score of Spence Children's Anxiety Scale was also higher. School children with obstructive sleep apnea with depressive symptoms were significantly higher than that in control. The scores of Autism Behaviour Checklist, Spence Children's Anxiety Scale, and Children's Depression Inventory in the obstructive sleep apnea group after surgery were significantly lower than that before surgery. Our study showed that the score of Spence Children's Anxiety Scale and Children's Depression Inventory had a close correlation with the illness course and hypoxia duration. The Spence Children's Anxiety Scale and Children's Depression Inventory scores are also closely associated with the Autism Behaviour Checklist score. These results suggest that obstructive sleep apnea may have a significant impact on autism symptoms, anxiety levels and depressive symptoms in children. We found that the longer the duration of the obstructive sleep apnea course and hypoxia, the greater the impact on anxiety level and depressive symptoms. The suspected autism symptoms, anxiety level and depressive symptoms in children with obstructive sleep apnea were also significantly correlated. Thus, early detection and timely treatment may often reverse the psychological and behavioural abnormalities caused by obstructive sleep apnea."

基金机构："Entrepreneurship and Innovation Support Program of Chongqing for overseas Scholars [CX2022118]; Natural Science Foundation of Chongqing [CSTB2022NSCQ-MSX1069, CSTC2020JCYJ-MSXMX0252]"

基金资助正文："the Entrepreneurship and Innovation Support Program of Chongqing for overseas Scholars, Grant/Award Number: CX2022118; the Natural Science Foundation of Chongqing, Grant/Award Numbers: CSTB2022NSCQ-MSX1069, CSTC2020JCYJ-MSXMX0252"