Prevalence and risk factors of acne scars in patients with acne vulgaris

作者全名："Liu, Lin; Xue, Yuzhou; Chen, Yangmei; Chen, Tingqiao; Zhong, Judan; Shao, Xinyi; Chen, Jin"

作者地址："[Liu, Lin; Chen, Yangmei; Chen, Tingqiao; Zhong, Judan; Shao, Xinyi; Chen, Jin] Chongqing Med Univ, Affiliated Hosp 1, Dept Dermatol, Chongqing, Peoples R China; [Xue, Yuzhou] Peking Univ Third Hosp, Inst Vasc Med, Dept Cardiol, Beijing, Peoples R China; [Chen, Jin] Chongqing Med Univ, Affiliated Hosp 1, Dept Dermatol, 1 Youyi Rd, Chongqing 400016, Peoples R China"

通信作者："Chen, J (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Dept Dermatol, 1 Youyi Rd, Chongqing 400016, Peoples R China."

来源：SKIN RESEARCH AND TECHNOLOGY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000999066800001

JCR分区：Q3

影响因子：2

年份：2023

卷号：29

期号：6

开始页：　

结束页：　

文献类型：Article

关键词：acne; acne scar; acne vulgaris; prevalence; risk factor

摘要："BackgroundAcne scar is a persistent complication of acne vulgaris. However, the prevalence and risk factors are still unclear. This study aimed to assess the global prevalence and risk factors of acne scars in patients with acne. Materials and methodsA systematic search of published studies in three databases was performed and the meta-analyses were conducted. ResultsFinally, we included 37 studies involving 24 649 acne patients. And, the pooled prevalence of acne scars in these patients was 47% (95% confidence interval [CI]: 38-56%). Besides, the differences in prevalence were observed based on the subgroup analysis for age, gender, acne severity, source of patients, and so on. Subsequently, we quantified the relationship of three risk factors with acne scars: male gender (odds ratio [OR]: 1.58, 95% CI: 1.19-2.09), positive family history of acne (OR: 2.73, 95% CI: 1.26-5.91), and acne severity (OR for moderate acne: 2.34, 95% CI: 1.54-3.57; OR for severe acne: 5.51, 95% CI: 2.45-12.41). ConclusionHerein, we found that 47% of acne patients suffered from acne scars and identified three risk factors: male gender, positive family history of acne, and acne severity. In order to reduce acne scarring, attention and effective therapy early in the course of acne is important."

基金机构：National Natural Science Foundation of China [n82073462]

基金资助正文：ACKNOWLEDGMENTS This study was supported by National Natural Science Foundation of China (grant number: n82073462).