Constructing a dummy-template adsorbent using magnetic molecular-imprinted chitosan for rapid enrichment of flavonoids compounds from Penthorum chinense Pursh

作者全名："Yang, Li-Li; Li, Ting; Yang, Dan-Dan; Li, Yan-Jun; He, Jia-Yuan; Zhou, Lian-Di; Zhang, Qi-Hui; Wang, Chong-Zhi; Yuan, Chun-Su"

作者地址："[Yang, Li-Li; Li, Ting; Yang, Dan-Dan; Li, Yan-Jun; He, Jia-Yuan; Zhang, Qi-Hui] Chongqing Univ, Sch Chem & Chem Engn, Chongqing 400044, Peoples R China; [Zhou, Lian-Di] Chongqing Med Univ, Basic Med Coll, Chongqing 400016, Peoples R China; [Zhang, Qi-Hui; Wang, Chong-Zhi; Yuan, Chun-Su] Univ Chicago, Tang Ctr Herbal Med Res, Chicago, IL 60637 USA; [Zhang, Qi-Hui; Wang, Chong-Zhi; Yuan, Chun-Su] Univ Chicago, Dept Anesthesia & Crit Care, Chicago, IL 60637 USA"

通信作者："Zhang, QH (通讯作者)，Chongqing Univ, Sch Chem & Chem Engn, Chongqing 400044, Peoples R China.; Zhou, LD (通讯作者)，Chongqing Med Univ, Basic Med Coll, Chongqing 400016, Peoples R China.; Zhang, QH (通讯作者)，Univ Chicago, Tang Ctr Herbal Med Res, Chicago, IL 60637 USA.; Zhang, QH (通讯作者)，Univ Chicago, Dept Anesthesia & Crit Care, Chicago, IL 60637 USA."

来源：MICROCHEMICAL JOURNAL

ESI学科分类：CHEMISTRY

WOS号：WOS:001002769600001

JCR分区：Q1

影响因子：4.9

年份：2023

卷号：191

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：Dummy template; Molecularly imprinted polymer; Naringenin; Penthorum chinense Pursh; Flavonoids

摘要："In this work, a novel dummy molecularly imprinted polymer (MIP/CS/Fe3O4) was successfully prepared for the selective enrichment of flavonoids in Penthorum chinense Pursh. The molecularly imprinted polymer was synthesized on the surface of chitosan-modified Fe3O4 nanoparticles with naringenin as the dummy template and then it was used as a solid adsorbent for the analyte enrichment. Compared with structural analogues, the MIP/CS/Fe3O4 presented quick binding kinetic behavior, satisfying selectivity and high adsorption capacity toward pinocembrin. The adsorption capacity and the imprinting factor of MIP/CS/Fe3O4 could reach 8.56 mg center dot g(-1) and 1.7, respectively. Finally, MIP/CS/Fe3O4 was applied to enrich flavonoids in the crude extract from Penthorum chinense Pursh and 11 flavonoids were successfully detected, indicating the MIP/CS/Fe3O4 was a promising adsorbent for separation and enrichment of flavonoids. Many favorable properties of the synthesized dummy molecularly imprinted polymer can also provide a new direction for the simultaneous enrichment of structural similarities."

基金机构："National Natural Science Foundation of China [81973451]; Fundamental and Frontier Research Fund of Chongqing [cstc2018jcyjAX0661, cstc2019jsyj-yzysbAX0020]; Science and Technology Research Program of Chongqing Municipal Education Commission [KJZD-K201800103]; Fundamental Research Funds for the Central Universities [2019CDYGYB027]; Graduate Research and Innovation Foundation of Chongqing [CYS18033]; Venture & Innovation Support Program for Chongqing Overseas Returnees; Tang Foundations"

基金资助正文："This work was financially supported by National Natural Science Foundation of China [No.81973451] ; Fundamental and Frontier Research Fund of Chongqing [No. cstc2018jcyjAX0661, No. cstc2019jsyj-yzysbAX0020] ; the Science and Technology Research Program of Chongqing Municipal Education Commission [No. KJZD-K201800103] ; Fundamental Research Funds for the Central Universities [No. 2019CDYGYB027] ; Graduate Research and Innovation Foundation of Chongqing [No. CYS18033] ; Venture & Innovation Support Program for Chongqing Overseas Returnees, and Tang Foundations."