"Biofabricated gold nanoparticles from Ammannia baccifera as potential antimicrobial, mosquito larvicidal activity, and alter immune response in zebrafish embryo"

作者全名："Suman, Thodhal Yoganandham; Jia, Huang-Jie; Yin, Supei; Wei, Xing-Yi; Hu, Huan; Bu, Ling-Kang; Yang, Guan; Pei, De-Sheng"

作者地址："[Suman, Thodhal Yoganandham; Jia, Huang-Jie; Wei, Xing-Yi; Hu, Huan; Bu, Ling-Kang; Yang, Guan; Pei, De-Sheng] Chongqing Med Univ, Sch Publ Hlth, Chongqing 400016, Peoples R China; [Yin, Supei] Chongqing Med Univ, Urinary Nephropathy Ctr, Affiliated Hosp 2, Chongqing 400072, Peoples R China"

通信作者："Pei, DS (通讯作者)，Chongqing Med Univ, Sch Publ Hlth, Chongqing 400016, Peoples R China."

来源：BIOMASS CONVERSION AND BIOREFINERY

ESI学科分类：ENGINEERING

WOS号：WOS:001002818500001

JCR分区：Q2

影响因子：3.5

年份：2023

卷号：　

期号：　

开始页：　

结束页：　

文献类型：Article; Early Access

关键词：Antibacterial activity; Gold nanoparticles; Immune response; Larvicidal activity; Zebrafish embryos

摘要："Gold nanoparticles (GNPs) are commonly utilized in biomedical science, but the potential application of green synthesized herb-based GNPs is elusive. Here, aqueous extracts of Ammannia baccifera were used to synthesize GNPs, and the properties of green synthesized GNPs were analyzed. Our results showed that these GNPs possessed larvicidal activity for Anopheles subpictus and Culex Quinquefasciatus, and antimicrobial activity for Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, and Bacillus subtilis. A rising dose of GNPs in zebrafish followed an increasing Au accumulation. Furthermore, the expression levels of immune-related genes were dramatically activated after exposure to these GNPs. To our knowledge, this is the first report on the potential application of the GNPs derived from A. baccifera extract."

基金机构：High-Level Talent Program of Chongqing Medical University [R4014]; Program of China-Sri Lanka Joint Center for Water Technology Research and Demonstration by Chinese Academy of Sciences (CAS)/China-Sri Lanka Joint Center for Education and Research by CAS

基金资助正文：We thank the support from the High-Level Talent Program of Chongqing Medical University (R4014 to D.S.P) and Program of China-Sri Lanka Joint Center for Water Technology Research and Demonstration by Chinese Academy of Sciences (CAS)/China-Sri Lanka Joint Center for Education and Research by CAS.