Advances in the molecular imaging of primary aldosteronism

作者全名："Ren, Xinyi; Cheng, Gang; Wang, Zhengjie"

作者地址："[Ren, Xinyi; Cheng, Gang; Wang, Zhengjie] Chongqing Med Univ, Affiliated Hosp 1, Dept Nucl Med, Chongqing 400016, Peoples R China"

通信作者："Cheng, G; Wang, ZJ (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Dept Nucl Med, Chongqing 400016, Peoples R China."

来源：ANNALS OF NUCLEAR MEDICINE

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001020171300001

JCR分区：Q2

影响因子：2.5

年份：2023

卷号：37

期号：8

开始页：433

结束页：441

文献类型：Review

关键词：Primary aldosteronism; Nuclide molecular imaging; Subtype diagnosis; Prognostic assessment

摘要："Primary aldosteronism (PA) is the most common cause of secondary hypertension. It predisposes to adverse outcomes such as nephrotoxicity and cardiovascular damage, which are mediated by direct harm from hypertension to the target organs. Accurate subtype diagnosis and localization are crucial elements in choosing the type of treatment for PA in clinical practice since the dominant side of aldosterone secretion in PA affects subsequent treatment options. The gold standard for diagnosing PA subtypes, adrenal venous sampling (AVS), requires specialized expertise, the invasive nature of the procedure and high costs, all of which delay the effective treatment of PA. Nuclide molecular imaging is non-invasive and has wider applications in the diagnosis and treatment of PA. This review aims to provide a summary of the application of radionuclide imaging in the diagnosis, treatment management and prognostic assessment of PA."

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