CRACK RESISTANCE CHARACTERISTICS OF MICROSTRUCTURE OF HAVERSIAN CORTICAL BONE

作者全名："Li, Yanhua; Li, Aihua"

作者地址："[Li, Yanhua] Chongqing Med Univ, Childrens Hosp, Minist Educ, China Int Sci & Technol,Chongqing Key Lab Translat, Chongqing 400014, Peoples R China; [Li, Aihua] Chongqing Univ, Canc Hosp, Key Lab Biorheol Sci & Technol, Minist Educ, Chongqing 400044, Peoples R China; [Li, Yanhua] Chongqing Canc Inst, Chongqing 400044, Peoples R China; [Li, Aihua] Chongqing Canc Hosp, Chongqing 400044, Peoples R China"

通信作者："Li, YH (通讯作者)，Chongqing Med Univ, Childrens Hosp, Minist Educ, China Int Sci & Technol,Chongqing Key Lab Translat, Chongqing 400014, Peoples R China.; Li, AH (通讯作者)，Chongqing Univ, Canc Hosp, Key Lab Biorheol Sci & Technol, Minist Educ, Chongqing 400044, Peoples R China.; Li, YH (通讯作者)，Chongqing Canc Inst, Chongqing 400044, Peoples R China.; Li, AH (通讯作者)，Chongqing Canc Hosp, Chongqing 400044, Peoples R China."

来源：JOURNAL OF MECHANICS IN MEDICINE AND BIOLOGY

ESI学科分类：MOLECULAR BIOLOGY & GENETICS

WOS号：WOS:001021296600001

JCR分区：Q4

影响因子：0.8

年份：2023

卷号：23

期号：5

开始页：　

结束页：　

文献类型：Article

关键词：Haversian cortical bone; osteon; cement line; stress intensity factor; fracture toughness

摘要："Background: The current research on crack propagation resistance characteristics of osteons is based on the single osteon model, which cannot reflect the interaction among osteons and the influence of material-property changes on the crack propagation. Moreover, the Haversian canal and the cement line were not included in the model, which could not reflect the influence of the true structural characteristics of the cortical bone on the microcracks.Objective: To investigate the effects of osteons, cement line and its material parameters on the stress intensity factor at the crack-tip based on theoretical formula calculation and finite element calculation.Results: The single osteon model, multi-osteon model and Haversian cortical bone model were established according to the microstructural characteristics of Haversian cortical bone. The calculation results of the first two models show that the ""soft"" osteon accelerates the crack propagation and the ""hard"" osteon hinders crack propagation, and the effect of multi-osteon model on a microcrack is significantly larger than that of single bone model. The calculation results of Haversian cortical bone model show that the stress intensity factors at both ends of the microcrack decreased when the distance from the ""soft"" osteon was within a certain range (1:5<d=R<2:5). The stress intensity factor of endpoint `a' in the crack-tip increases sharplywhen the microcrack is close to the osteonConclusions: The analysis results of the three models present that the microcrack propagation is affected by the material properties as well as the quantity of osteon, and the cement line is conductive to enhance the fracture toughness of the cortical bone."

基金机构：Chongqing scientific research institutes performance incentive guidance special [Cstc2020jxjl0093]

基金资助正文：This work was supported by the Chongqing scientific research institutes performance incentive guidance special (Grant No. Cstc2020jxjl0093).