Access to alpha-Vinyl ss-Alkynyl Enals via an Organocatalytic Deconjugation-Aldol Condensation Sequence
作者全名：Quan Yiwen; Jiang Xinhui; Li Wenjun; Wang Jian
作者地址："[Quan Yiwen] Chongqing Med Univ, Coll Clin Med 1, Chongqing 400016, Peoples R China; [Jiang Xinhui] Chongqing Med Univ, Sch Pharm, Chongqing 400016, Peoples R China; [Li Wenjun; Wang Jian] Tsinghua Univ, Sch Pharmaceut Sci, Beijing 100084, Peoples R China"
通信作者："Jiang, XH (通讯作者)，Chongqing Med Univ, Sch Pharm, Chongqing 400016, Peoples R China.; Wang, J (通讯作者)，Tsinghua Univ, Sch Pharmaceut Sci, Beijing 100084, Peoples R China."
来源：CHINESE JOURNAL OF ORGANIC CHEMISTRY
ESI学科分类：CHEMISTRY
WOS号：WOS:001028786600016
JCR分区：Q3
影响因子：1.8
年份：2023
卷号：43
期号：6
开始页：2120
结束页：2125
文献类型：Article
关键词：alpha-vinyl ss-alkynyl enal; deconjugation-aldol condensation; organocatalysis; enamine
摘要："A new green synthetic route to alpha-vinyl ss-alkynyl enals from alpha,ss-unsaturated aldehydes and ynals is developed. This protocol allows a broad substrate scope and mild conditions. Furthermore, a proposed mechanism of a deconjugation-aldol condensation process is discussed in detail."
基金机构："National Natural Science Foundation of China [21871160, 21672121, 22071130]"
基金资助正文："Project supported by the National Natural Science Foundation of China (Nos. 21871160, 21672121, 22071130)."
