"Analysis of carotid plaque risk factors in a population at high risk of stroke in Yubei District, Chongqing, China"

作者全名："Zou, Yujia; Zhang, Xiaohui; Bu, Xiaoqing; Zhang, Ziyan; Wu, Yi; Ren, Yanni; Mu, Lihong"

作者地址："[Zou, Yujia; Bu, Xiaoqing; Zhang, Ziyan; Wu, Yi; Ren, Yanni; Mu, Lihong] Chongqing Med Univ, Sch Publ Hlth, Dept Epidemiol, Chongqing 400016, Peoples R China; [Zhang, Xiaohui] Yubei Dist Ctr Dis Control & Prevent, Dept Chron Dis, Chongqing 401120, Peoples R China"

通信作者："Zou, YJ (通讯作者)，Chongqing Med Univ, Sch Publ Hlth, Dept Epidemiol, Chongqing 400016, Peoples R China."

来源：JOURNAL OF STROKE & CEREBROVASCULAR DISEASES

ESI学科分类：NEUROSCIENCE & BEHAVIOR

WOS号：WOS:001037863400001

JCR分区：Q3

影响因子：2

年份：2023

卷号：32

期号：8

开始页：　

结束页：　

文献类型：Article

关键词：Stroke; Carotid plaque; High-risk population; Low-density lipoprotein cholesterol; Glycosylated hemoglobin; Hypertension

摘要："Objective: To establish a scientific foundation for focused stroke prevention and treatment efforts by comprehending the risk variables connected to carotid plaque formation in adults over 40 who are at high risk of stroke in Yubei District, Chongq-ing, China. Methods: By comparing the differences in carotid plaque formation between people of different ages, smoking, blood pressure levels, low-density lipo-protein levels, and glycosylated hemoglobin levels, questionnaires and physical exams were performed on a random sample of permanent residents aged 40 years in three communities in Yubei District, Chongqing, China. The goal was to investi-gate the risk factors associated with carotid plaque formation in the population. Results: The incidence of carotid plaque gradually increased in the study population as age, blood pressure, low-density lipoprotein, and glycosylated hemoglobin levels increased. The difference in carotid plaque formation between people of different ages, smoking, blood pressure levels, low-density lipoprotein levels, and glycosy-lated hemoglobin levels was statistically significant (p<0.05). The findings of the multifactorial logistic regression analysis revealed that there was a tendency for the risk of developing carotid plaque to rise with age; the risk of developing carotid pla-que in hypertensive patients was (OR=1.41,95% CI: 1.03-1.93); the population of smokers was (OR=2.01,95%CI:1.33-3.05); the low-density lipoprotein cholesterol borderline increased group was (OR=1.94,95%CI:1.03-3.66); the low-density lipo-protein cholesterol elevated group was (OR=2.71,95%CI: 1.26-5.84); glycosylated hemoglobin elevated group was (OR=1.40,95%CI: 1.01-1.94) (p<0.05). Conclusion: Age, smoking, blood pressure, low-density lipoprotein, and glycosy-lated hemoglobin are all associated with carotid plaque formation in those over 40 who are at high risk of stroke. As a result, health education for residents needs to be strengthened to raise knowledge of carotid plaque prevention."

基金机构：National Health Commission Stroke Screening and Intervention Project (Proj- ect) [Z135080000022]

基金资助正文："Sources of Funding This study was conducted as part of the National Health Commission Stroke Screening and Intervention Project (Proj- ect No. Z135080000022) . The National Health Commission was involved in the design of this study, but not in the imple- mentation, data collection, analysis and writing of the article."