An Update on Temporal Bone Paragangliomas

作者全名："Zhong, Shixun; Zuo, Wenqi"

作者地址："[Zhong, Shixun; Zuo, Wenqi] Chongqing Med Univ, Dept Otolaryngol, Affiliated Hosp 1, 1 Youyi Rd, Chongqing 400016, Peoples R China"

通信作者："Zhong, SX (通讯作者)，Chongqing Med Univ, Dept Otolaryngol, Affiliated Hosp 1, 1 Youyi Rd, Chongqing 400016, Peoples R China."

来源：CURRENT TREATMENT OPTIONS IN ONCOLOGY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001044836100001

JCR分区：Q2

影响因子：3.8

年份：2023

卷号：　

期号：　

开始页：　

结束页：　

文献类型：Review; Early Access

关键词：Temporal bone; Paraganglioma; Surgical treatment; Radiotherapy

摘要："Opinion statementTemporal bone paragangliomas (TBPs) are indolent, classically benign and highly vascular neoplasms of the temporal bone. There are two types of TBPs, tympanomastoid paragangliomas (TMPs) and tympanojugular paragangliomas (TJPs). The most common symptoms are hearing loss and pulsatile tinnitus. Diagnostic workup, besides conventional physical and laboratory examinations, includes biochemical testing of catecholamine and genetic testing of SDHx gene mutations as well as radiological examination. Although surgery is traditionally the mainstay of treatment, it is challenging due to the close proximity of tumor to critical neurovascular structures and thus the high risk of complications, especially in patients with advanced lesions. Radiotherapy and active surveillance have been increasingly recommended for selected patients. Decision on treatment should be made comprehensively. Curative effect depends on various factors. Long-term follow-up with clinical, laboratory, and radiological examinations is essential for all patients."

基金机构："Key Project of Technical Innovation, Application and Development in Health Field of Chongqing Science and Technology Bureau [CSTC2021jscx-gksb-N0012]"

基金资助正文："This work was supported by the Key Project of Technical Innovation, Application and Development in Health Field of Chongqing Science and Technology Bureau (CSTC2021jscx-gksb-N0012)."