Multi-dimensional influence of pediatric epilepsy on children and their families: A cross-sectional study

作者全名："Wu, You; Zhang, Rui; Tang, Jianyong; Li, Xia; Wang, Yan; Li, Taoli; Wu, Fang; Dou, Xiangjun; Wang, Dong; Jiang, Li"

作者地址："[Wu, You; Jiang, Li] Chongqing Med Univ, Natl Clin Res Ctr Child Hlth & Disorders, Key Lab Child Dev & Disorders, Dept Neurol,Childrens Hosp,Minist Educ,China Int S, 136 Zhongshan 2nd Rd, Chongqing 400014, Peoples R China; [Wu, You; Zhang, Rui; Li, Xia; Wang, Yan; Li, Taoli; Wu, Fang; Dou, Xiangjun; Wang, Dong] Xi An Jiao Tong Univ, Xian Childrens Hosp, Dept Neurol, Affiliated Childrens Hosp, 69 Xijuyuan Lane, Xian 710003, Shaanxi, Peoples R China; [Tang, Jianyong] Xi An Jiao Tong Univ, Xian Childrens Hosp, Dept Lab Med, Affiliated Childrens Hosp, Xian, Shaanxi, Peoples R China"

通信作者："Jiang, L (通讯作者)，Chongqing Med Univ, Natl Clin Res Ctr Child Hlth & Disorders, Key Lab Child Dev & Disorders, Dept Neurol,Childrens Hosp,Minist Educ,China Int S, 136 Zhongshan 2nd Rd, Chongqing 400014, Peoples R China.; Wang, D (通讯作者)，Xi An Jiao Tong Univ, Xian Childrens Hosp, Dept Neurol, Affiliated Childrens Hosp, 69 Xijuyuan Lane, Xian 710003, Shaanxi, Peoples R China."

来源：EPILEPSY & BEHAVIOR

ESI学科分类：NEUROSCIENCE & BEHAVIOR

WOS号：WOS:001046968300001

JCR分区：Q2

影响因子：2.3

年份：2023

卷号：146

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：Epilepsy; Family burden of disease; Anxiety; Depression; Quality of Life

摘要："Objective: In this study, we aimed to evaluate the effects of pediatric epilepsy on family burden, parental anxiety, depression states, and quality of life of both parents and children.Methods: The study was undertaken between March and December 2021 using an online questionnaire that included the Family Burden Scale of Disease, the 7-item Generalized Anxiety Disorder scale, the 9 item Patient Health Questionnaire, the WHO Quality of Life Scale (WHOQOL-BREF), and the PedsQL 4.0 Generic Core Scales (parent-proxy report).Results: A total of 288 parents of children aged 2-18 years were included. Overall, 94.8% of the participating families experienced high levels of disease burden, 67.0% of parents suffered from anxiety states, 57.0% suffered from depression states, and 56.2% of children with epilepsy suffered from comorbid neuropsychiatric symptoms. The mean WHOQOL-BREF score for parental quality of life was 53.7 & PLUSMN; 12.8, while the median PedsQL score for children's quality of life was 65.4 (49.6-81.7). Parental depression states contributed the most to family burden and parental quality of life, whereas comorbidities of epilepsy contributed the most to children's quality of life. Seizure frequency significantly influenced parental anxiety states, and family burden was the most significant predictor of parental depression states.Conclusion: Heavy disease burden, anxiety states, and depression states are prevalent in families with children suffering from epilepsy, and most have a poor quality of life. There is a need for greater focus on the quality of life of this patient population and their caregivers, as well as increased resources to help combat anxiety, depression, and poor quality of life.& COPY; 2023 Published by Elsevier Inc."

基金机构：Xi'an Children's Hospital Youth Pro-ject [2021H01]

基金资助正文："Funding The work was supported by Xi'an Children's Hospital Youth Pro-ject (Grant Nos. 2021H01) . The funders were not involved in research design, data collection, analysis, or interpretation."