Preterm birth and detection of common respiratory pathogens among pediatric pneumonia

作者全名："Wang, Xin-Rui; Du, Juan; Zhang, Shan-Shan; Zhang, Wan-Xue; Zhang, Xiao-Ai; Lu, Qing-Bin; Ren, Luo; Liu, Wei; Liu, En-Mei"

作者地址："[Wang, Xin-Rui; Du, Juan; Zhang, Shan-Shan; Zhang, Wan-Xue; Lu, Qing-Bin] Peking Univ, Sch Publ Hlth, Dept Lab Sci & Technol, Beijing 100191, Peoples R China; [Wang, Xin-Rui; Du, Juan; Zhang, Shan-Shan; Zhang, Wan-Xue; Lu, Qing-Bin] Peking Univ, Vaccine Res Ctr, Sch Publ Hlth, Beijing 100191, Peoples R China; [Wang, Xin-Rui; Du, Juan; Zhang, Shan-Shan; Zhang, Wan-Xue; Lu, Qing-Bin] Peking Univ, Global Ctr Infect Dis & Policy Res, Beijing 100191, Peoples R China; [Wang, Xin-Rui; Du, Juan; Zhang, Shan-Shan; Zhang, Wan-Xue; Lu, Qing-Bin] Peking Univ, Global Hlth & Infect Dis Grp, Beijing 100191, Peoples R China; [Zhang, Xiao-Ai; Liu, Wei] Beijing Inst Microbiol & Epidemiol, State Key Lab Pathogen & Biosecur, Beijing, Peoples R China; [Lu, Qing-Bin] Peking Univ, Minist Educ, Key Lab Epidemiol Major Dis, Beijing 100191, Peoples R China; [Ren, Luo; Liu, En-Mei] Chongqing Med Univ, Childrens Hosp, Dept Resp Med, Chongqing 400014, Peoples R China; [Liu, Wei] Anhui Med Univ, Sch Publ Hlth, Hefei, Peoples R China"

通信作者："Lu, QB (通讯作者)，Peking Univ, Sch Publ Hlth, Dept Lab Sci & Technol, Beijing 100191, Peoples R China.; Lu, QB (通讯作者)，Peking Univ, Vaccine Res Ctr, Sch Publ Hlth, Beijing 100191, Peoples R China.; Lu, QB (通讯作者)，Peking Univ, Global Ctr Infect Dis & Policy Res, Beijing 100191, Peoples R China.; Lu, QB (通讯作者)，Peking Univ, Global Hlth & Infect Dis Grp, Beijing 100191, Peoples R China.; Liu, W (通讯作者)，Beijing Inst Microbiol & Epidemiol, State Key Lab Pathogen & Biosecur, Beijing, Peoples R China.; Lu, QB (通讯作者)，Peking Univ, Minist Educ, Key Lab Epidemiol Major Dis, Beijing 100191, Peoples R China.; Ren, L; Liu, EM (通讯作者)，Chongqing Med Univ, Childrens Hosp, Dept Resp Med, Chongqing 400014, Peoples R China.; Liu, W (通讯作者)，Anhui Med Univ, Sch Publ Hlth, Hefei, Peoples R China."

来源：ISCIENCE

ESI学科分类：　

WOS号：WOS:001062969000001

JCR分区：Q1

影响因子：4.6

年份：2023

卷号：26

期号：9

开始页：　

结束页：　

文献类型：Article

关键词：　

摘要："Pneumonia complicated by preterm birth is related to adverse clinical sequelae from the neonatal period to childhood. Children with pneumonia during 2009-2021 were enrolled at the Children's Hospital of Chongqing Medical University. Altogether 20 respiratory pathogens were detected and compared. Among 8,206 children, 779 were in the preterm group with 246 of early-preterm and 533 of late preterm. The positive rates for all viral pathogens were comparable between the preterm group and the full-term group. For bacterial pathogens, higher positive rates for Escherichia coli and Klebsiella pneumoniae were observed in the preterm group. Severe pneumonia developed in 16.52% of all, which was higher in the preterm group than in the full-term group. A significantly higher rate of severe pneumonia was observed in the early-preterm group compared to the late-preterm group. Preterm birth has an impact on the detection of bacterial pathogens in children and is a risk factor for severe pneumonia."

基金机构："China Mega-Project for Infectious Diseases Grant [2018ZX10101003, 2018ZX10713002]; Joint Research Fund for Beijing Natural Science Foundation and Haidian Original Innovation [L202007]; Research and Development Program of China [2022YFC2704900]"

基金资助正文："This work was supported by China Mega-Project for Infectious Diseases Grant (grant numbers 2018ZX10101003, 2018ZX10713002) ; Joint Research Fund for Beijing Natural Science Foundation and Haidian Original Innovation (grant number L202007) ; and Research and Development Program of China (grant number 2022YFC2704900) ."