A retrospective study on the physical growth of twins in the first year after birth

作者全名："Pan, Ting; Huang, Yanru; Cheng, Qian; Chen, Li; Hu, Yan; Dai, Ying; Liu, Xiao; Jiang, Zhiyang; Zhong, Yuanfeng; Zhang, Zhanzhan; Chen, Qian; Zhang, Qian; Zhang, Xuan"

作者地址："[Pan, Ting; Huang, Yanru; Cheng, Qian; Chen, Li; Hu, Yan; Dai, Ying; Liu, Xiao; Jiang, Zhiyang; Zhong, Yuanfeng; Zhang, Zhanzhan; Chen, Qian; Zhang, Qian; Zhang, Xuan] Chongqing Med Univ, Chongqing Growth Dev & Mental Hlth Ctr Children &, Natl Clin Res Ctr Child Hlth & Disorders, Dept Child Hlth Care,Childrens Hosp,Minist Educ,Ke, Chongqing, Peoples R China; [Huang, Yanru] Luzhou Peoples Hosp, Dept Child Hlth Care, Luzhou, Sichuan, Peoples R China"

通信作者："Zhang, X (通讯作者)，Chongqing Med Univ, Chongqing Growth Dev & Mental Hlth Ctr Children &, Natl Clin Res Ctr Child Hlth & Disorders, Dept Child Hlth Care,Childrens Hosp,Minist Educ,Ke, Chongqing, Peoples R China."

来源：FRONTIERS IN NUTRITION

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001076357300001

JCR分区：Q2

影响因子：4

年份：2023

卷号：10

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：appropriate for gestational age; catch up growth; growth and development; physical anthropology; small for gestational age

摘要："ObjectivesThis study analyzed the physical growth of small for gestational age (SGA) and appropriate for gestational age (AGA) twins up to one year after birth.MethodsWeight, length, and head circumference data of 0-1 year-old twins were collected from the Child Health Care System from 2010 to 2019. Physical data were presented as Z-scores. Five parameters - growth level of weight, body length, head circumference, growth velocity, and body proportion (weight for length) were compared in twins.ResultsA total of 3,909 cases were collected (22.61% SGA, 77.39% AGA). 1. In both groups, WAZ (Weight for age z-score), HCZ (Head circumference for age z-score), and LAZ (Length for age z-score) increased more rapidly in the first 6 months. By one year of age, WAZ, HCZ, and LAZ had reached the normal range, but none had reached the average level of normal singleton children. 2. The mean values of WAZ, HCZ, and LAZ in the AGA group were between -1 and 0, and between -2 and - 1 in the SGA group, in the first year after birth. The SGA group lagged significantly behind the AGA group. The LAZ score of SGA and AGA was lower than the WAZ and HCZ scores. 3. The proportion of preterm AGA was the largest in twins, and the growth rate of preterm AGA was the fastest. Preterm twins had greater growth potential than term twins. However, the growth level of preterm SGA was always low. 4. The WFLZ (Weight for length z-score) in each group was approximately close to 0. The WFLZ of SGA was smaller than that of AGA twins at most time points. After 4 months of age, the WFLZ of twins had a downward trend. The WFLZ of preterm SGA approached -1 at approximately 1 year old.ConclusionThe physical growth of SGA and AGA in twins in the first year can reach the normal range but cannot reach the average level of normal singleton children. More attention should be paid to SGA in twins, especially preterm SGA. We should give proper nutritional guidance after 4 months of age to ensure the appropriate body proportion (weight for length) of SGA in twins.Clinical trial registrationwww.chictr.org.cn, CTR2000034761."

基金机构：This study was supported by the Chongqing Health Commission Science and Health Joint Medical Scientific Research Project (Yu Weifa [2021] 47-2022MSXM100). [[2021] 47-2022MSXM100]; Chongqing Health Commission Science and Health Joint Medical Scientific Research Project (Yu Weifa)

基金资助正文：This study was supported by the Chongqing Health Commission Science and Health Joint Medical Scientific Research Project (Yu Weifa [2021] 47-2022MSXM100).