Key to the Treatment of Primary Aldosteronism in Secondary Hypertension: Subtype Diagnosis

作者全名："Zuo, Rui; Liu, Shuang; Xu, Lu; Pang, Hua"

作者地址："[Zuo, Rui; Liu, Shuang; Xu, Lu; Pang, Hua] Chongqing Med Univ, Dept Nucl Med, Affiliated Hosp 1, 1 Youyi Rd, Chongqing 400016, Peoples R China"

通信作者："Pang, H (通讯作者)，Chongqing Med Univ, Dept Nucl Med, Affiliated Hosp 1, 1 Youyi Rd, Chongqing 400016, Peoples R China."

来源：CURRENT HYPERTENSION REPORTS

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001076497400001

JCR分区：Q1

影响因子：3.9

年份：2023

卷号：　

期号：　

开始页：　

结束页：　

文献类型：Review; Early Access

关键词：Primary aldosteronism; Subtype diagnosis; Secondary hypertension; AVS; PET/CT

摘要："Purpose of ReviewPrimary aldosteronism (PA) is a leading global cause of secondary hypertension. Subtyping diagnosis of PA is the key to surgery, but accurate classification of PA is crucial but challenging in clinical diagnosis and treatment. The purpose of this review is to provide a summary of current literature and propose subtyping diagnosis flow chart to help us classify PA quickly and accurately.Recent FindingsEarly diagnosis and accurate typing are essential for the timely treatment and appropriate management of PA. For most patients, adrenal venous sampling (AVS) is the central choice for typing diagnosis, but AVS is invasive and difficult to promote effectively. CT can help identify unilateral typical adenomas in select patients to avoid AVS. New radionuclide imaging has shown value in the diagnosis and classification of PA, which distinguishes adrenocortical hyperplasia from adenoma and can replace AVS in some patients.SummaryAccurately diagnosing unilateral PA is crucial for determining the appropriate treatment strategy for PA. The simple flow chart of PA subtyping diagnosis based on the current literature needs to be verified and evaluated by follow-up researches."

基金机构："Program for Youth Innovation in Future Medicine, Chongqing Medical University [0301020499QC-W0117]"

基金资助正文："This work was funded by the Program for Youth Innovation in Future Medicine, Chongqing Medical University (project number: 0301020499QC-W0117)"