Predicting Postoperative Complications in Patients Undergoing Colorectal Surgery with an Enhanced Recovery Pathway

作者全名："Ren, Li; Lv, Feng; Min, Su; Jin, Juying; Qin, Peipei"

作者地址："[Ren, Li; Lv, Feng; Min, Su; Jin, Juying; Qin, Peipei] Chongqing Med Univ, Dept Psychiat, Affiliated Hosp 1, 1 Youyi Rd, Chongqing 400016, Peoples R China"

通信作者："Min, S (通讯作者)，Chongqing Med Univ, Dept Psychiat, Affiliated Hosp 1, 1 Youyi Rd, Chongqing 400016, Peoples R China."

来源：WORLD JOURNAL OF SURGERY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001082577900003

JCR分区：Q2

影响因子：2.3

年份：2023

卷号：　

期号：　

开始页：　

结束页：　

文献类型：Article; Early Access

关键词：　

摘要："BackgroundReducing postoperative complications is the essential requirement of the enhanced recovery after surgery (ERAS) program. This study aimed to identify the key perioperative components affecting postoperative complications in patients undergoing colorectal surgery with ERAS.MethodsThis retrospective cohort study included all patients who underwent major colorectal surgery with ERAS program between February 2019 and June 2020, all perioperative information was retrieved from a database. Univariate and multivariate logistic regression analyses were used to identify predictors for complications within 30 days postoperatively, and a nomogram model was drawn to visualize the model. Receiver operating characteristic curve (ROC) and calibration curve were used to evaluate the model performance.ResultsWe enrolled 649 patients and 72 patients (11.1%) had at least 1 complication within 30 days postoperatively. Multivariate analyses showed that minimally invasive surgery [odds ratio (OR) 0.323; 95% confidence interval (CI) 0.168-0.620] was associated with a decreased of the complications. However, preoperative anemia (OR 2.052; 95%CI 1.073-3.928) and old age (OR 1.927; 95%CI 1.022-3.632) were independent risk factors for complications within 30 days postoperatively. The C-index of the nomogram was 0.735 (95%CI 0.694-0.776). Calibration curve showed a relatively good agreement between predicted value and observed outcome. In the validation set, the nomogram showed an area under the ROC curve of 0.729 (95%CI 0.680-0.778).ConclusionsThis study suggests that preoperative anemia, old age and minimally invasive surgery may individually influence the prognosis of patients undergoing major colorectal surgery with an enhanced recovery pathway.Trial registration Clinical Trial Registry (number: ChiCTR2000037513).ConclusionsThis study suggests that preoperative anemia, old age and minimally invasive surgery may individually influence the prognosis of patients undergoing major colorectal surgery with an enhanced recovery pathway.Trial registration Clinical Trial Registry (number: ChiCTR2000037513)."

基金机构：Chongqing Social Science Planning Project [2021PY27]; Chongqing Technology Innovation and Application Project [cstc2018jscx-msybX0139]

基金资助正文：This study was supported by Chongqing Social Science Planning Project (2021PY27) and the Chongqing Technology Innovation and Application Project (No. cstc2018jscx-msybX0139).