A Clinical Analysis of Prognosis and Patient-Reported Outcomes of Oncoplastic Breast-Conserving Surgery for Early Breast Cancer: A Retrospective Cohort Study

作者全名："Ren, Jh; Wang, Yuanyuan; Zhang, Xiang; Cheng, Qiao; Wang, Kang; Liu, Qiang; Tang, Renxi; Yang, Ling; Gong, Junge; Xu, Jiawei; Li, Hongyuan"

作者地址："[Ren, Jh] Chongqing Hlth Ctr Women & Children, Chongqing, Peoples R China; [Ren, Jh] Chongqing Med Univ, Women & Childrens Hosp, Chongqing, Peoples R China; [Wang, Yuanyuan; Zhang, Xiang; Cheng, Qiao; Tang, Renxi; Yang, Ling; Gong, Junge; Xu, Jiawei; Li, Hongyuan] Chongqing Med Univ, Affiliated Hosp 2, Dept Breast & Thyroid Surg, Chongqing, Peoples R China; [Wang, Kang] Karolinska Inst Stockholm, Dept Oncol Pathol, Stockholm, Sweden; [Liu, Qiang] Peoples Hosp Dazu, Chongqing, Peoples R China"

通信作者："Li, HY (通讯作者)，Chongqing Med Univ, Affiliated Hosp 2, Dept Breast & Thyroid Surg, Chongqing, Peoples R China."

来源：AESTHETIC PLASTIC SURGERY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001083746200001

JCR分区：Q2

影响因子：2

年份：2023

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期号：　

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结束页：　

文献类型：Article; Early Access

关键词：Oncoplastic; Breast-conserving surgery; Patient-reported outcomes; Aesthetic outcomes; Prognosis

摘要："Purpose Approximately 25-30% of patients suffer from breast deformity and/or asymmetry after conventional breast-conserving surgery (CBCS). Generally, it is thought that oncoplastic breast-conserving surgery (OBCS) results in an improved cosmetic result; however, studies comparing the prognosis and aesthetic outcomes of CBCS and OBCS in early breast cancer (EBC) are inadequate.Methods A total of 143 patients were included in this retrospective cohort study; 53 underwent OBCS and 90 underwent CBCS. The resected weight, complications, esthetic results, patient satisfaction, and recurrence rate were compared between the groups. Patient-reported outcomes (PRO) were assessed by the BREAST-Q questionnaire.Results The mean age of the patients in OBCS group was 43.8 years. This was younger than that in CBCS group (49.1 years, p < 0.001). Postoperative complications (11.3% vs. 8.9%, p = 0.64) and re-excision (5.7% vs. 6.7%, p > 0.99) rates were similar. The OBCS group had higher breast satisfaction and psychosocial well-being than the CBCS group (75 vs. 63, p < 0.001 and 84 vs. 77, p = 0.05); however, sexual well-being (56 vs. 66, p = 0.05) and physical well-being (65 vs. 76, p < 0.001) were worse in OBCS. After 42.3 (range: 12.6-69.2)-month median follow-up, no difference in event-free survival (EFS) was demonstrated between the groups (p = 0.13).Conclusion Although OBCS has the better aesthetic outcomes and identical oncological safety in comparison with CBCS, the sexual and physical well-being in OBCS are not improved for Asian patients. Hence, choosing an appropriate procedure may be more important for the typically small to moderate-sized breasts characteristic of Asian females unlike Westerners.Level of Evidence IV This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266."

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