Green Synthesis of Low-Glycemic Amylose-Lipid Nanocomposites by High-Speed Homogenization and Formulation into Hydrogel

作者全名："Khan, Nasir Mehmood; Uddin, Misbah; Falade, Ebenezer Ola; Khan, Farman Ali; Wang, Jian; Shafique, Muhammad; Alnemari, Reem M.; Abduljabbar, Maram H.; Ahmad, Shujaat"

作者地址："[Khan, Nasir Mehmood] Shaheed Benazir Bhutto Univ, Dept Agr, Upper Dir 18000, Khyber Pakhtunk, Pakistan; [Uddin, Misbah; Khan, Farman Ali] Shaheed Benazir Bhutto Univ, Dept Chem, Upper Dir 18000, Khyber Pakhtunk, Pakistan; [Falade, Ebenezer Ola] Chinese Acad Agr Sci, Inst Food Sci & Technol, Beijing 100193, Peoples R China; [Wang, Jian] Chongqing Coll Tradit Chinese Med, Dept Chinese Mat Med, Chongqing 402760, Peoples R China; [Wang, Jian] Chongqing Med Univ, Coll Tradit Chinese Med, Chongqing 400016, Peoples R China; [Shafique, Muhammad] Shaqra Univ, Coll Pharm, Dept Pharmaceut Sci, Shaqra 15571, Saudi Arabia; [Alnemari, Reem M.] Taif Univ, Coll Pharm, Dept Pharmaceut & Pharmaceut Technol, POB 11099, Taif 21944, Saudi Arabia; [Abduljabbar, Maram H.] Taif Univ, Coll Pharm, Dept Pharmacol & Toxicol, POB 11099, Taif 21944, Saudi Arabia; [Ahmad, Shujaat] Shaheed Benazir Bhutto Univ, Dept Pharm, Upper Dir 18000, Khyber Pakhtunk, Pakistan"

通信作者："Shafique, M (通讯作者)，Shaqra Univ, Coll Pharm, Dept Pharmaceut Sci, Shaqra 15571, Saudi Arabia.; Ahmad, S (通讯作者)，Shaheed Benazir Bhutto Univ, Dept Pharm, Upper Dir 18000, Khyber Pakhtunk, Pakistan."

来源：MOLECULES

ESI学科分类：CHEMISTRY

WOS号：WOS:001089525800001

JCR分区：Q2

影响因子：4.2

年份：2023

卷号：28

期号：20

开始页：　

结束页：　

文献类型：Article

关键词：amylose-lipid nanocomposite; hydrogel; rheology; glycemic index (GI); absorption capacity

摘要："In this research, we focused on the production of amylose-lipid nanocomposite material (ALN) through a green synthesis technique utilizing high-speed homogenization. Our aim was to investigate this novel material's distinctive physicochemical features and its potential applications as a low-glycemic gelling and functional food ingredient. The study begins with the formulation of the amylose-lipid nanomaterial from starch and fatty acid complexes, including stearic, palmitic, and lauric acids. Structural analysis reveals the presence of ester carbonyl functionalities, solid matrix structures, partial crystallinities, and remarkable thermal stability within the ALN. Notably, the ALN exhibits a significantly low glycemic index (GI, 40%) and elevated resistance starch (RS) values. The research extends to the formulation of ALN into nanocomposite hydrogels, enabling the evaluation of its anthocyanin absorption capacity. This analysis provides valuable insights into the rheological properties and viscoelastic behavior of the resulting hydrogels. Furthermore, the study investigates anthocyanin encapsulation and retention by ALN-based hydrogels, with a particular focus on the influence of pH and physical cross-link networks on the uptake capacity presenting stearic-acid (SA) hydrogel with the best absorption capacity. In conclusion, the green-synthesized (ALN) shows remarkable functional and structural properties. The produced ALN-based hydrogels are promising materials for a variety of applications, such as medicine administration, food packaging, and other industrial purposes."

基金机构："The authors would like to thank the Deanship of Scientific Research at Shaqra University, Shaqra, Saudi Arabia, for supporting this work.; Deanship of Scientific Research at Shaqra University, Shaqra, Saudi Arabia"

基金资助正文："The authors would like to thank the Deanship of Scientific Research at Shaqra University, Shaqra, Saudi Arabia, for supporting this work."