Lymphoma-related intussusception in children: diagnostic challenges and clinical characteristics

作者全名："Zhang, Rensen; Zhang, Minjie; Deng, Ruyu; Li, Yao; Guo, Chunbao"

作者地址："[Zhang, Rensen; Zhang, Minjie; Deng, Ruyu; Li, Yao] Chongqing Med Univ, Childrens Hosp, Chongqing, Peoples R China; [Zhang, Rensen; Li, Yao; Guo, Chunbao] Chongqing Med Univ, Chongqing Hlth Ctr Women & Children, Dept Pediat, 120 Longshan Rd, Chongqing 401147, Peoples R China; [Guo, Chunbao] Chongqing Med Univ, Women & Childrens Hosp, Dept Pediat, Chongqing, Peoples R China"

通信作者："Guo, CB (通讯作者)，Chongqing Med Univ, Chongqing Hlth Ctr Women & Children, Dept Pediat, 120 Longshan Rd, Chongqing 401147, Peoples R China.; Guo, CB (通讯作者)，Chongqing Med Univ, Women & Childrens Hosp, Dept Pediat, Chongqing, Peoples R China."

来源：EUROPEAN JOURNAL OF PEDIATRICS

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001090466800004

JCR分区：Q1

影响因子：3

年份：2023

卷号：　

期号：　

开始页：　

结束页：　

文献类型：Article; Early Access

关键词：Intussusception; Lymphoma; Children; Diagnosis; Surgical intervention

摘要："Intussusception is a common cause of acute abdominal pain in children and the most frequent cause of intestinal obstruction in infants. Although often idiopathic, it can stem from conditions like lymphoma. This study delves into lymphoma-related intussusception in children, aiming to enhance early detection and management. A retrospective review encompassed children admitted from 2012 to 2023 with intussusception due to intestinal lymphoma. Demographic, clinical, and imaging data were meticulously extracted and analyzed. The study included 31 children in the lymphoma-related intussusception group. Contrasted with non-lymphoma-related cases, the patients of lymphoma-related intussusception were notably older (median age: 87 months vs. 18.5 months), predominantly male, and demonstrated protracted abdominal pain. Ultrasound unveiled mesenteric lymph node enlargement and distinct intra-abdominal masses; enema reduction success rates were notably diminished. Detecting lymphoma-related intussusception remains intricate. Age, prolonged symptoms, and distinctive ultrasound findings can arouse suspicion. Timely surgical intervention, based on preoperative imaging, proves pivotal for accurate diagnosis.Conclusion: Swift identification of lymphoma-related intussusception, distinguished by unique clinical and ultrasound features, is imperative for timely intervention and treatment. Further research is warranted to refine diagnostic approaches.What is Known:center dot Intussusception in pediatric patients can be caused by a wide spectrum of underlying diseases including lymphoma.center dot Early Identifying the exact underlying cause of intussusception is crucial for tailored therapy, however often challenging and time-consuming.What is New:center dot Lymphoma-related intussusception may present with increased abdominal fluid accumulation, intestinal obstruction, and a higher likelihood of failed reduction during enema procedures.center dot For high-risk children, repeated ultrasound examinations or further investigations may be necessary to confirm the diagnosis."

基金机构：We would like to express our appreciation to Children's Hospital of Chongqing Medical University for their support during the research process.; Children's Hospital of Chongqing Medical University

基金资助正文：We would like to express our appreciation to Children's Hospital of Chongqing Medical University for their support during the research process.