Development and validation of a simple-to-use nomogram for predicting the delayed radiographic recovery in children with mycoplasma pneumoniae pneumonia complicated with atelectasis

作者全名："Luo, Yonghan; Dai, Jihong; Tang, Guojing; He, Shan; Fu, Wenlong"

作者地址："[Luo, Yonghan] Kunming Childrens Hosp, Dept Infect Dis 2, Kunming, Yunnan, Peoples R China; [Dai, Jihong; He, Shan; Fu, Wenlong] Chongqing Med Univ, Natl Clin Res Ctr Child Hlth & Disorders, China Int Sci & Technol Cooperat Base Child Dev &, Chongqing Key Lab Pediat,Dept Resp Dis,Minist Educ, Chongqing, Peoples R China; [Tang, Guojing] Chongqing Med Univ, Natl Clin Res Ctr Child Hlth & Disorders, Dept Crit Care Med, Minist Educ,Key Lab Child Dev & Disorders,Children, Chongqing, Peoples R China; [Dai, Jihong] Chongqing Med Univ, Dept Resp Dis, Childrens Hosp, 136,2nd Rd, Chongqing 400014, Peoples R China"

通信作者："Dai, JH (通讯作者)，Chongqing Med Univ, Dept Resp Dis, Childrens Hosp, 136,2nd Rd, Chongqing 400014, Peoples R China."

来源：JOURNAL OF INVESTIGATIVE MEDICINE

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001092507900005

JCR分区：Q1

影响因子：2.5

年份：2023

卷号：71

期号：7

开始页：722

结束页：729

文献类型：Article

关键词：Nomogram; mycoplasma pneumoniae pneumonia; atelectasis; children

摘要："This study aimed to develop and validate a simple-to-use nomogram for predicting the delayed radiographic recovery in children with mycoplasma pneumoniae pneumonia (MPP) complicated with atelectasis. A retrospective study of 306 children with MPP complicated with atelectasis was performed at the Children's Hospital of Chongqing Medical University from February 2017 to March 2020.The patients were divided into recovery group and delayed recovery group based on chest CT scan 1 month after discharge. A least absolute shrinkage and selection operator (LASSO) regression model was used to identify the optimal predictors, and the predictive nomogram was plotted by multivariable logistic regression. The nomogram was assessed by calibration, discrimination, and clinical utility. LASSO regression analysis identified that lactate dehydrogenase (LDH), duration of illness prior to bronchoalveolar lavage (BAL), systemic glucocorticoid use and extrapulmonary complications were the optimal predictors for delayed radiographic recovery. The nomogram was plotted by the four predictors. The area under the Receiver Operating Characteristic (ROC) curve of the nomogram was 0.840 (95% CI = 784 similar to 0.896) in the training set and 0.833 (95% CI = 0.8737 similar to 0.930) in the testing set. The calibration curve demonstrated that the nomogram was well-fitted, and decision curve analysis (DCA) showed that the nomogram was clinically beneficial. This study developed and validated a simple-to-use nomogram for predicting delayed radiographic recovery in children with MPP complicated with atelectasis. This might be generally applied in clinical practice."

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