"Application of spectral CT in diagnosis, classification and prognostic monitoring of gastrointestinal cancers: progress, limitations and prospects"

作者全名："Hong, Yuqin; Zhong, Lijuan; Lv, Xue; Liu, Qiao; Fu, Langzhou; Zhou, Daiquan; Yu, Na"

作者地址："[Hong, Yuqin; Lv, Xue; Liu, Qiao; Fu, Langzhou; Zhou, Daiquan; Yu, Na] Chongqing Med Univ, Affiliated Hosp 3, Dept Radiol, Gener Hosp, Chongqing, Peoples R China; [Zhong, Lijuan] Peoples Hosp Leshan, Dept Radiol, Leshan, Peoples R China"

通信作者："Zhou, DQ; Yu, N (通讯作者)，Chongqing Med Univ, Affiliated Hosp 3, Dept Radiol, Gener Hosp, Chongqing, Peoples R China."

来源：FRONTIERS IN MOLECULAR BIOSCIENCES

ESI学科分类：BIOLOGY & BIOCHEMISTRY

WOS号：WOS:001097636700001

JCR分区：Q2

影响因子：3.9

年份：2023

卷号：10

期号：　

开始页：　

结束页：　

文献类型：Review

关键词：gastrointestinal cancers; spectral CT; multi-parameter imaging; diagnosis; efficacy evaluation

摘要："Gastrointestinal (GI) cancer is the leading cause of cancer-related deaths worldwide. Computed tomography (CT) is an important auxiliary tool for the diagnosis, evaluation, and prognosis prediction of gastrointestinal tumors. Spectral CT is another major CT revolution after spiral CT and multidetector CT. Compared to traditional CT which only provides single-parameter anatomical diagnostic mode imaging, spectral CT can achieve multi-parameter imaging and provide a wealth of image information to optimize disease diagnosis. In recent years, with the rapid development and application of spectral CT, more and more studies on the application of spectral CT in the characterization of GI tumors have been published. For this review, we obtained a substantial volume of literature, focusing on spectral CT imaging of gastrointestinal cancers, including esophageal, stomach, colorectal, liver, and pancreatic cancers. We found that spectral CT can not only accurately stage gastrointestinal tumors before operation but also distinguish benign and malignant GI tumors with improved image quality, and effectively evaluate the therapeutic response and prognosis of the lesions. In addition, this paper also discusses the limitations and prospects of using spectral CT in GI cancer diagnosis and treatment."

基金机构："The author(s) declare that no financial support was received for the research, authorship, and/or publication of this article."

基金资助正文："NY acknowledges support from the Chongqing Medical University (No. YJSZHYX202011).r The author(s) declare that no financial support was received for the research, authorship, and/or publication of this article."