Development and Validation of a Nomogram to Predict the Risk of Recurrent Lower Extremity Radiating Pain Within 1 Week Following Full-Endoscopic Lumbar Discectomy

作者全名："Zhong, Dian; Wang, Yang; Lin, Lu; Cheng, Si; Zhao, Guo Sheng; Wang, Li Yuan; Liu, Yang; Ke, Zhen Yong"

作者地址："[Zhong, Dian; Wang, Yang; Lin, Lu; Cheng, Si; Zhao, Guo Sheng; Wang, Li Yuan; Liu, Yang; Ke, Zhen Yong] Chongqing Med Univ, Affiliated Hosp 2, Dept Spine Surg, Chongqing, Peoples R China"

通信作者："Wang, Y (通讯作者)，Chongqing Med Univ, Affiliated Hosp 2, Dept Spine Surg, Chongqing, Peoples R China."

来源：WORLD NEUROSURGERY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001101840800001

JCR分区：Q2

影响因子：1.9

年份：2023

卷号：179

期号：　

开始页：E348

结束页：E358

文献类型：Article

关键词：Full-endoscopic lumbar discectomy; Lumbar disc herniation; Nomogram; Postoperative pain; Prediction model; Recurrent radicular pain; Risk factors

摘要："BACKGROUND: Accurately predicting the risk of lower extremity (LE) radiating pain after surgery is an important endeavor for spinal surgeons. Our study aimed to identify risk factors for LE radiating pain after decompression with full-endoscopic lumbar discectomy (FELD) and develop a nomogram. METHODS: We retrospectively reviewed the medical data of patients with lumbar disc herniation who underwent FELD. Two hundred thirty-five patients diagnosed at our hospital from January 2015 to December 2020 were used for model development. The independent risk factors for LE radiating pain after surgery were determined by least absolute shrinkage and selection operator logistic regression and multivariate logistic regression analysis. A nomogram was developed to predict the risk of LE radiating pain based on independent risk factors. Receiver operating characteristic curve, calibration curve, and decision curve analyses were used to evaluate the predictive performance. The nomogram was further verified by an independent cohort. RESULTS: Three hundred seventy-five patients were enrolled in this study, with 102 patients in the training cohort reporting LE radiating pain after FELD, while 133 patients did not. In the validation cohort, 57 patients reported LE radiating pain after FELD, while 83 patients did not. The model was established by multivariate logistic regression analysis. The risk factors included a higher Michigan State University classification of herniated discs, increased disease course, increased time of surgery, reduced lateral recess width, and an interlaminar surgical approach, compared to transforaminal approach. The Cindices and the area under the receiver operating characteristic curve of the predictive model demonstrated good discrimination. Good predictive performance and accuracy were also observed in the validation cohort. CONCLUSIONS: A novel nomogram for predicting recurrent LE radiating pain within 1 week after FELD was established and validated. More aggressive pain management strategies should be considered for patients at high risk of LE radiating pain after surgery, as predicted by this model."

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