"Construction of vaccination network and influencing factors: a case study of Chongqing, China"

作者全名："Li, Jianing; Fan, Jie; Zhu, Ling; Wu, Xiaohua; Luo, Chunyu; Wang, Wei"

作者地址："[Li, Jianing; Fan, Jie; Zhu, Ling; Wang, Wei] Chongqing Med Univ, Sch Publ Hlth, Chongqing, Peoples R China; [Fan, Jie; Zhu, Ling; Wu, Xiaohua; Luo, Chunyu] Nanan Dist Ctr Dis Control & Prevent, Chongqing, Peoples R China"

通信作者："Wang, W (通讯作者)，Chongqing Med Univ, Sch Publ Hlth, Chongqing, Peoples R China."

来源：HUMANITIES & SOCIAL SCIENCES COMMUNICATIONS

ESI学科分类：　

WOS号：WOS:001105828200002

JCR分区：Q1

影响因子：3.7

年份：2023

卷号：10

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：　

摘要："Vaccination is a fundamental tool in preventing infectious diseases. However, due to the wide array of vaccines available, comprehending the entire vaccine landscape can be a daunting task. To tackle this complexity, this study employs advanced network analysis methods capable of capturing the intricate relationships within multivariate datasets. The objective is to investigate how the vaccination landscape has evolved both before and after the COVID-19 pandemic. This study examined vaccination data in the Nanan District of Chongqing, China, spanning from 2016 to 2022. Additionally, the network topological characteristics were computed and scrutinized across 2326 sliding windows. The investigation focused on assessing alterations in the topological structure of the vaccination network before and after the COVID-19 pandemic, encompassing analyses at both macro and mesoscale levels. Furthermore, at the micro level, this study delved into the correlation degrees of selected vaccine nodes within the vaccination network. The analysis unveiled that the correlation and activity within the vaccination network showed a noticeable enhancement in strength in the wake of the COVID-19 pandemic, especially during the spring and winter months. However, the community structure and the average interactions between vaccines displayed a diminishing trend post-pandemic. Among the analyzed vaccines, the HepA vaccine emerged as the one with the highest average node-degree centrality rank. A closer examination of the node-degree centrality ranking chart within the vaccination network disclosed fluctuations in the rankings of various vaccine types across different time periods and seasons. In contrast, vaccines incorporated into NIP exhibited a remarkable degree of consistency, which is attributed to children adhering to a fixed vaccination schedule, rendering NIP vaccines less susceptible to disruptions and enhancing their stability within the vaccination network. This study offers valuable insights into the dynamics of the vaccination network, shedding light on the impact of the COVID-19 pandemic, seasonal variations, and the ever-shifting correlation patterns among different vaccine types. These discoveries enrich our comprehension of vaccination trends and have the potential to guide forthcoming endeavors aimed at refining vaccination strategies and enhancing public health outcomes, not only in the Nanan District but also in analogous settings."

基金机构："This research was supported by the Science and Technology Research Program of Chongqing Municipal Education Commission (No. KJQN202200429), the Program for Youth Innovation in Future Medicine, Chongqing Medical University (No. W0150), and the Intelligent M [KJQN202200429]; Science and Technology Research Program of Chongqing Municipal Education Commission [W0150]; Program for Youth Innovation in Future Medicine, Chongqing Medical University [ZHYX202223]; Intelligent Medicine Research Project of Chongqing Medical University"

基金资助正文："This research was supported by the Science and Technology Research Program of Chongqing Municipal Education Commission (No. KJQN202200429), the Program for Youth Innovation in Future Medicine, Chongqing Medical University (No. W0150), and the Intelligent Medicine Research Project of Chongqing Medical University (No. ZHYX202223)."