Comparison of Postoperative Outcome and Prognosis Among Laparoscopic Left Colectomy and Laparoscopic Sigmoidectomy in Sigmoid Colon Cancer Patients: A Propensity Score Matching Study

作者全名："Tao, Wei; Liu, Fei; Cheng, Yu-Xi; Zhang, Bin; Liu, Xiao-Yu; Zhang, Wei; Peng, Dong"

作者地址："[Tao, Wei; Liu, Fei; Cheng, Yu-Xi; Zhang, Bin; Liu, Xiao-Yu; Zhang, Wei; Peng, Dong] Chongqing Med Univ, Affiliated Hosp 1, Dept Gastrointestinal Surg, Chongqing, Peoples R China; [Tao, Wei] Army Med Univ, Xinqiao Hosp, Dept Gen Surg, Chongqing, Peoples R China; [Cheng, Yu-Xi] Fudan Univ, Zhongshan Hosp, Dept Gen Surg, Shanghai, Peoples R China; [Peng, Dong] Chongqing Med Univ, Affiliated Hosp 1, Dept Gastrointestinal Surg, 1 Youyi Rd, Chongqing 400016, Peoples R China"

通信作者："Peng, D (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Dept Gastrointestinal Surg, 1 Youyi Rd, Chongqing 400016, Peoples R China."

来源：CANCER CONTROL

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001107810600001

JCR分区：Q3

影响因子：2.5

年份：2023

卷号：30

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：sigmoid colon cancer; laparoscopic left colectomy; laparoscopic sigmoidectomy; prognosis

摘要："Purpose The purpose of this study was to investigate the effect of laparoscopic left colectomy (LLC) and laparoscopic sigmoidectomy (LSD) on short-term outcomes and prognosis of sigmoid colon cancer (SCC) patients using propensity score matching (PSM).Methods In this retrospective study, the SCC patients who underwent LLC or LSD surgery were collected from a single clinical center from Jan 2011 to Dec 2019. Short-term outcomes and prognosis were compared between patients who received LSD surgery and LLC surgery.Results A total of 356 patients were included in this study. After 1:1 PSM analysis, there were 50 patients who underwent LLC surgery and 50 patients who underwent LSD surgery left in this study. No significant difference was found in baseline characteristics after PSM (P > .05). In comparison with the LLC surgery group, the LSD surgery group had shorter operation time (P = .003) after PSM. Moreover, the surgical procedure was not an independent predictor for overall survival (OS) (P = .918, 95% CI = .333-2.688) and disease-free survival DFS (P = .730, 95% CI = .335-2.150), but age (OS: P = .009, 95% CI = 1.010-1.075; DFS: P = .014, 95% CI = 1.007-1.061) and tumor stage (OS: P = .004, 95% CI = 1.302-3.844; DFS: P < .01, 95% CI = 1.572-4.171) were the independent risk factors for OS and DFS in SCC patients.Conclusion There was no significant difference between the two surgical procedures for prognosis of SCC patients. However, the possible reasons for changing the surgical procedures should be cautious by surgeons."

基金机构："We acknowledge all the authors whose publications are referred in our article. We thank Xun Lei, a statistician, for the substantial work in the statistical methods. And we thank Melissa Davis for linguistic editing and proofreading during the preparation"

基金资助正文："We acknowledge all the authors whose publications are referred in our article. We thank Xun Lei, a statistician, for the substantial work in the statistical methods. And we thank Melissa Davis for linguistic editing and proofreading during the preparation of this manuscript."