Rescue endovascular thrombectomy in patients with progressive ischemic stroke within 24-72 h: A retrospective propensity score matched cohort study

作者全名："Wang, Yanchun; Shu, Jianzhong; Tao, Minghua; Tang, Mingshan; Pan, Chende; Zhen, Dinghao; Wang, Jie"

作者地址："[Wang, Yanchun; Tao, Minghua; Tang, Mingshan; Pan, Chende; Zhen, Dinghao; Wang, Jie] Chongqing Med Univ, Dept Neurol, Banan Hosp, 659 Yunan Rd, Chongqing 401320, Peoples R China; [Wang, Yanchun; Tao, Minghua; Tang, Mingshan; Pan, Chende; Zhen, Dinghao; Wang, Jie] Peoples Hosp Chongqing Banan Dist, 659 Yunan Rd, Chongqing 401320, Peoples R China; [Shu, Jianzhong] Chongqing Hosp Tradit Chinese Med, Dept Neurol, 6 Seventh Branch Rd, Chongqing 400011, Peoples R China"

通信作者："Wang, J (通讯作者)，Chongqing Med Univ, Dept Neurol, Banan Hosp, 659 Yunan Rd, Chongqing 401320, Peoples R China.; Wang, J (通讯作者)，Peoples Hosp Chongqing Banan Dist, 659 Yunan Rd, Chongqing 401320, Peoples R China."

来源：INTERDISCIPLINARY NEUROSURGERY-ADVANCED TECHNIQUES AND CASE MANAGEMENT

ESI学科分类：　

WOS号：WOS:001114519100001

JCR分区：Q4

影响因子：0.4

年份：2023

卷号：34

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：Rescue endovascular thrombectomy; Progressive ischemic stroke; Large vessel occlusion; Propensity score matching

摘要："Purpose: Currently, the prediction of progressive ischemic stroke (PIS) caused by large proximal artery occlusion (LVO) is not well developed. The main aim of the study is to check the effectiveness of endovascular thrombectomy(EVT) in patients with PIS and LVO in the anterior circulation.Methods: This multicenter retrospective cohort study involved two comprehensive stroke centres having two therapeutic approaches to manage patients with minor, mild, or acute ischemic stroke harbouring LVO. Some patients who experienced early neurologic deterioration (END) were either given the best medical care (BMM) or immediate rescue endovascular thrombectomy (RET) followed by BMM. Clinical outcomes, including good prognosis defined as 90-day modified Ranking Scale (mRS) <= 2, mortality, and symptomatic intracerebral hemorrhagic (sICH) rate were compared between two groups.Results: The study included 103 patients, including 48 patients in the RET + BMM group and 55 patients in the BMM group, and each group included 35 patients after propensity score matching. Compared to the BMM group, RET-treated patients had lower 90-day mRS scores at discharge (57.14% vs. 37.14%, p < 0.001). No significant differences in mortality (p = 0.315) and symptomatic intracranial haemorrhage (p = 0.487) were found. Similar results were obtained after propensity score matching.Conclusion: RET appears to be safe and feasible in patients with PIS due to LVO within 24-72 h. Further prospective, clinical, randomized controlled studies are warranted to validate these findings."

基金机构：Chongqing medical scientific research project (Joint project of Chongqing Health Commission and Science and Technology Bureau) [2020MSXM092]

基金资助正文：This study was supported by the Chongqing medical scientific research project (Joint project of Chongqing Health Commission and Science and Technology Bureau) (2020MSXM092) .