Impact of left atrial diameter on all-cause mortality of patients with STEMI undergoing primary percutaneous coronary intervention

作者全名："Wang, Kai; Zeng, Deli; Chen, Zijun; Yu, Wei"

作者地址："[Wang, Kai; Zeng, Deli; Chen, Zijun] Chongqing Med Univ, Yongchuan Hosp, Dept Cardiol, Chongqing, Peoples R China; [Chen, Zijun; Yu, Wei] Chongqing Med Univ, Affiliated Hosp 2, Dept Cardiol, Chongqing, Peoples R China"

通信作者："Yu, W (通讯作者)，Chongqing Med Univ, Affiliated Hosp 2, Dept Cardiol, Chongqing, Peoples R China."

来源：SAUDI MEDICAL JOURNAL

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001117595300001

JCR分区：Q2

影响因子：1.7

年份：2023

卷号：44

期号：12

开始页：1260

结束页：1268

文献类型：Article

关键词：heart atrial; myocardial infarction; prognosis; mortality

摘要："Objectives: To evaluating the predictive significance of the left atrial diameter in acute ST elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI). Methods: The STEMI population came from 2 retrospective cohorts with 1097 patients, cohorts A (YongChuan Hospital) and cohorts B (Taizhou First People's Hospital). Within 3 days (cohort A) or 5 days (cohort B) post-PCI, patients underwent ultrasound evaluations. Cohort A was segmented into quartile categories based on eft atrial diameter (LAd) (Q1 to Q4). The odds ratios (ORs) for overall mortality were assessed using logistic regression. Cohort B was used for sensitivity analysis. Results: During follow-up period, 226 (20.6%) patients experienced endpoint. In cohort A, univariable odds ratios were 2.68 (95%CI 1.11 similar to 6.89), 5.32 (95%CI 2.46 similar to 12.83) and 11.92 (95%CI 5.78 similar to 27.92), while multivariate ORs were 2.25 (95%CI 0.82 similar to 6.55), 5.09 (95%CI 2.12 similar to 13.56), and 15.05 (95%CI 6.58 similar to 39.09) in Q2 to Q4 group, respectively, compared with Q1 group (p for trend <0.001). Upon subgroup evaluation, the correlation between LAd and the likelihood of overall mortality was more pronounced in patients having a left ventricular ejection fraction (LVEF) between 40% and 50%, and those with LVEF >= 50%, in contrast to those with LVEF <40% (p for interaction <0.001). Conclusion: Left atrial diameter is indicative of the long-term overall mortality risk in STEMI patients post-PCI, particularly in those with an LVEF >= 40%."

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