Point-of-care testing of infectious diseases: recent advances

作者全名："Shang, Meiyun; Guo, Jiuchuan; Guo, Jinhong"

作者地址："[Shang, Meiyun; Guo, Jiuchuan; Guo, Jinhong] Chongqing Med Univ, Coll Lab Med, MOE Key Lab Lab Med Diagnost, 1 Yixueyuan Rd, Chongqing 400016, Peoples R China; [Guo, Jinhong] Univ Shanghai JiaoTong, Sch Cyber Secur, Shanghai, Peoples R China"

通信作者："Guo, JH (通讯作者)，Chongqing Med Univ, Coll Lab Med, MOE Key Lab Lab Med Diagnost, 1 Yixueyuan Rd, Chongqing 400016, Peoples R China.; Guo, JH (通讯作者)，Univ Shanghai JiaoTong, Sch Cyber Secur, Shanghai, Peoples R China."

来源：SENSORS & DIAGNOSTICS

ESI学科分类：　

WOS号：WOS:001127519300001

JCR分区：Q2

影响因子：3.5

年份：2023

卷号：2

期号：5

开始页：1123

结束页：1144

文献类型：Review

关键词：　

摘要："Infectious diseases have seriously threatened human health and caused enormous losses to the global economy. Rapid and accurate diagnosis of pathogens is crucial to the timely treatment of patients, improvement of their prognosis, and containment of disease transmission. The conventional methods for detecting pathogens are usually performed in well-equipped clinical laboratories that rely on sophisticated equipment and well-trained personnel. In addition, a series of pre-analytical procedures, such as long transport time, may bias test results and delay turnaround times (TAT), which are particularly detrimental to infectious disease control in resource-constrained areas. Advances in multidisciplinary technologies, shifts in health management models, and increased awareness of disease prevention have considerably driven the development of the point-of-care testing (POCT) market. Many portable, low-cost, and rapid POCT devices have been designed to promote health management, control disease spread, and improve patients' prognosis. This review focuses on a comprehensive summary of recently developed POCT methods for infectious diseases such as acquired immunodeficiency syndrome (AIDS), Zika virus disease, Coronavirus disease 2019 (COVID-19), Ebola virus disease (EVD), and malaria, highlights the utilization of different POCT devices in these diseases and reflects on the potential value of the internet of medical things (IoMT), big data, and artificial intelligence (AI) in the next-generation smart POCT. Finally, future perspectives, discussion and conclusions on detecting infectious diseases with POCT devices are listed. Next-generation POCT devices for infectious diseases will improve disease management."

基金机构：National Natural Science Foundation of China [62122017]; National Natural Science Foundation of China

基金资助正文："This work was supported by National Natural Science Foundation of China [grant numbers 62122017, 2017]."