Willis covered stent treatment for internal carotid artery pseudoaneurysm: A meta-analysis of efficacy and safety

作者全名:"Tan, Jiahe; Song, Rui; Luo, Siyue; Su, Jun; Ma, Yinrui; Qin, Baoping; He, Zhaohui"

作者地址:"[Tan, Jiahe; Su, Jun; Ma, Yinrui; He, Zhaohui] Chongqing Med Univ, Affiliated Hosp 1, Dept Neurosurg, 1 Youyi Rd, Chongqing 400016, Peoples R China; [Song, Rui] Chongqing Med Univ, Dept Infect Dis, Affiliated Hosp 2, Chongqing 401336, Peoples R China; [Luo, Siyue] Chongqing Med Univ, Clin Coll 2, Clin Med, Chongqing 400042, Peoples R China; [Qin, Baoping] Peoples Hosp Shi Zhu Tu Jia Zu Autonomous Cty, Dept Neurosurg, Chongqing 409100, Peoples R China"

通信作者:"He, ZH (通讯作者),Chongqing Med Univ, Affiliated Hosp 1, Dept Neurosurg, 1 Youyi Rd, Chongqing 400016, Peoples R China.; Qin, BP (通讯作者),Peoples Hosp Shi Zhu Tu Jia Zu Autonomous Cty, Dept Neurosurg, Chongqing 409100, Peoples R China."

来源:HELIYON

ESI学科分类: 

WOS号:WOS:001133404700001

JCR分区:Q1

影响因子:3.4

年份:2023

卷号:9

期号:12

开始页: 

结束页: 

文献类型:Article; Early Access

关键词:Willis covered stent; Pseudoaneurysm; Efficacy; Safety; Meta -analysis

摘要:"Background: Pseudoaneurysm (PSA) of internal carotid artery is a rare but severe cerebrovascular disease and difficult to repair surgically. A novel medical device called Willis covered stent (WCS) has been created especially for the treatment of complex cerebrovascular diseases. However, the efficacy and safety of WCS therapy for PSA are still debatable. Additional substantial proof is needed.Methods: To find research pertaining to WCS treatment for PSA, a systematic review of literature was conducted in the Medline, Embase, Web of Science, CNKI, Wanfang, and CBM databases. The results comprising the data of intraoperative situation, postoperative situation, and follow-up were then included in a meta-analysis.Results: The criteria were met by 11 noncomparative studies with 152 patients and 157 PSAs. Technical success rate was nearly 100 % (>0.999 (95 % confidence interval (CI), 0.958, 1.000)), complete occlusion rate was 97.8 % (95 % CI, 0.932, 1.000), and side branch occlusion rate was 0.5 % (95 % CI, 0.001, 0.045). The rates of acute in-stent thrombosis (<0.001 (95 % CI, 0.000, 0.013)) and hemorrhage (<0.001 (95 % CI, 0.000, 0.005)) were both less than 0.1 %. In postoperative situation, surgery-related mortality rate was less than 0.1 % (<0.001 (95 % CI, 0.000, 0.005)). The rates of recurrence (<0.001 (95 % CI, 0.000, 0.002)) and parent artery stenosis (<0.001 (95 % CI, 0.000, 0.008)) were both less than 0.1 %, while late in-stent stenosis occurred in 1.3 % (95 % CI, 0.000, 0.053) of patients. In the end, 98.5 % (95 % CI, 0.943, 1.000) of patients had a good outcome. Conclusion: The application of WCS could be effective and safe for PSAs. The findings of this study could serve as a reference for upcoming clinical trials."

基金机构:National Natural Science Foundation of China [NSFC 81870927]; Natural Science Foundation Project of Chongqing Science and Technology Commission [CSTB2023NSCQ-MSX0112]

基金资助正文:This study was supported by the National Natural Science Foundation of China (NSFC 81870927) and the Natural Science Foundation Project of Chongqing Science and Technology Commission (CSTB2023NSCQ-MSX0112) .