Cubic cobalt ferrite anchored on graphene sheets for non-enzymatic electrochemical detection of 17α-ethinyl estradiol in environmental and biological samples

作者全名："Li, Yanting; Zhu, Shu; Zhao, Hua; Xiong, Yan; Gong, Tao; Tao, Yanru; Li, Jin; Hu, Jiangling; Wang, Hongmei; Jiang, Xinhui"

作者地址："[Li, Yanting; Zhao, Hua; Xiong, Yan; Tao, Yanru; Li, Jin; Hu, Jiangling; Wang, Hongmei; Jiang, Xinhui] Chongqing Med Univ, Chongqing Res Ctr Pharmaceut Engn, Sch Pharm, Chongqing 400016, Peoples R China; [Zhu, Shu] Chongqing Med Univ, Lab Teaching & Management Ctr, Lab Pharm & Chem, Chongqing 400016, Peoples R China; [Gong, Tao] Nanchong Cent Hosp, Nanchong Key Lab Individualized Drug Therapy, Nanchong 637000, Sichuan, Peoples R China; [Li, Jin] Chongqing Med Univ, Dept Pharm, Childrens Hosp Affiliated, Chongqing 400014, Peoples R China; [Wang, Hongmei] Chongqing Lybon Pharm Tech Co Ltd, Fu Pharmaceut Grp, Chongqing 401121, Peoples R China; [Jiang, Xinhui] Chongqing Med Univ, Chongqing Res Ctr Pharmaceut Engn, Sch Pharm, 1 Yixueyuan Rd, Chongqing 400016, Peoples R China"

通信作者："Jiang, XH (通讯作者)，Chongqing Med Univ, Chongqing Res Ctr Pharmaceut Engn, Sch Pharm, 1 Yixueyuan Rd, Chongqing 400016, Peoples R China."

来源：JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING

ESI学科分类：　

WOS号：WOS:001136226100001

JCR分区：Q1

影响因子：7.4

年份：2024

卷号：12

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Ethinyl estradiol; Cobalt ferrite; Graphene sheet; Electrochemical detection; Square wave voltammetry

摘要："Recently, the endocrine interference of endocrine disruptors on the environment and aquatic organisms has been a hot topic. Ethinyl estradiol (EE2) is an estrogen endocrine disruptor and one of the most widely used in-gredients in oral contraceptives, resulting in high emissions and environmental pollution. Therefore, it is urgent to construct a non-enzymic, simple and low-cost sensor to detect EE2 in environmental and biological samples. We successfully prepared cobalt ferric oxide with anti-spinel structure and reduced graphene oxide composite (CoFe2O4/RGO) using hydrothermal synthesis, which decorated on the glass carbon electrode (GCE) to detect EE2. The morphological structure of CoFe2O4/RGO composites was studied by FESEM, HRTEM, EDX, FT-IR, XRD, and XPS techniques. Additionally, the experimental conditions were optimized and the oxidation mecha-nism of EE2 was explained theoretically and EE2 was detected by CV, EIS, and SWV, which displayed a fantastic current response of EE2. The electrochemical results illustrated that the prepared sensor has good selectivity, high sensitivity, a wide linear range of 0.05-100 mu M, and a lower detection limit of 42 nM. Finally, the prac-ticability of the sensor to detect EE2 in real samples was also studied and obtained a satisfactory recovery."

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