The Effect of Liver Cirrhosis on Patients Undergoing Cardiac Surgery

作者全名："Liu, Fei; Li, Zi-Wei; Liu, Xu-Rui; Liu, Xiao-Yu; Yang, Jun"

作者地址："[Liu, Fei; Li, Zi-Wei; Liu, Xu-Rui; Liu, Xiao-Yu] Chongqing Med Univ, Affiliated Hosp 1, Dept Gastrointestinal Surg, Chongqing, Peoples R China; [Yang, Jun] Chongqing Med Univ, Affiliated Hosp 1, Dept Anesthesiol, Chongqing, Peoples R China"

通信作者："Yang, J (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Dept Anesthesiol, Chongqing, Peoples R China."

来源：GLOBAL HEART

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001141188300002

JCR分区：Q2

影响因子：3

年份：2023

卷号：18

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：liver cirrhosis; cardiac surgery; complications

摘要："The aim of this study was to investigate the impact of liver cirrhosis (LC) on postoperative complications and long-term outcomes in patients who underwent cardiac surgery. Three databases, including PubMed, Embase, and the Cochrane Library, were searched on July 24, 2022. A total of 1,535,129 patients were enrolled in the seven included studies for analysis. According to our analysis, LC was a risk factor for postoperative overall complications (OR = 1.48, 95% CI = 1.21 to 1.81, I-2 = 90.35%, P = 0.00 < 0.1). For various complications, more patients developed pulmonary (OR = 1.86, 95% CI = 1.21 to 2.87, I-2 = 90.79%, P = 0.00 < 0.1), gastrointestinal (OR = 2.03, 95% CI = 1.32 to 3.11, I-2 = 0.00%, P = 0.00 < 0.05), renal (OR = 2.20, 95% CI = 1.41 to 3.45, I-2 = 91.60%, P = 0.00 < 0.1), neurological (OR = 1.14, 95% CI = 1.03 to 1.26, I-2 = 7.35%, P = 0.01 < 0.05), and infectious (OR = 2.02, 95% CI = 1.17 to 3.50, I-2 = 92.37%, P = 0.01 < 0.1) complications after surgery in the LC group. As for cardiovascular (OR = 1.07, 95% CI = 0.85 to 1.35, I-2 = 75.23%, P = 0.58 > 0.1) complications, there was no statistical significance between the 2 groups. As for long-term outcomes, we found that in-hospital death (OR = 2.53, 95% CI = 1.86 to 3.20, I-2 = 44.58%, P = 0.00 < 0.05) and death (OR = 3.31, 95% CI = 1.54 to 5.07, I-2 = 93.81%, P = 0.00 < 0.1) in the LC group were higher than the non-LC group. LC was a risk factor for cardiac surgery. Patients with LC who would undergo cardiac surgery should be fully assessed for the risks of cardiac surgery. Similarly, the surgeon should assess the patient's liver function before surgery."

基金机构："Chongqing Natural Science Foundation [CSTB2022NSCQ-MSX0075]; Program for Youth Innovation in Future Medicine, Chongqing Medical University [W0168]"

基金资助正文："This study was supported by Chongqing Natural Science Foundation project (CSTB2022NSCQ-MSX0075) and Program for Youth Innovation in Future Medicine, Chongqing Medical University (W0168)."