Clinical characteristics of congenital heart defects in mild congenital anorectal malformation: single-centre experience

作者全名："Feng, Wei; Zhang, Minjie; Hou, Jinping; Die, Xiaohong; Wang, Yi; Liu, Rong"

作者地址："[Feng, Wei; Zhang, Minjie; Hou, Jinping; Die, Xiaohong; Wang, Yi; Liu, Rong] Chongqing Med Univ, Childrens Hosp, Det Gen & Neonatal Surg, Chongqing, Peoples R China; [Feng, Wei; Zhang, Minjie; Hou, Jinping; Die, Xiaohong; Wang, Yi; Liu, Rong] Natl Clin Res Ctr Child Hlth & Disorders, Minist Educ, Chongqing Key Lab Struct Birth Defect & Reconstruc, Key Lab Child Dev & Disorders, Chongqing, Peoples R China"

通信作者："Wang, Y; Liu, R (通讯作者)，Chongqing Med Univ, Childrens Hosp, Det Gen & Neonatal Surg, Chongqing, Peoples R China.; Wang, Y; Liu, R (通讯作者)，Natl Clin Res Ctr Child Hlth & Disorders, Minist Educ, Chongqing Key Lab Struct Birth Defect & Reconstruc, Key Lab Child Dev & Disorders, Chongqing, Peoples R China."

来源：BMC PEDIATRICS

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001146299900003

JCR分区：Q2

影响因子：2.4

年份：2024

卷号：24

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Congenital heart defect; Congenital anorectal malformation; Clinical characteristic; Sex difference

摘要："ObjectiveTo analyze the clinical characteristics and types of congenital heart defect (CHD) in mild congenital anorectal malformation (CARM), namely the rectoperineal and rectovestibular fistulas.MethodsThe retrospective study of 183 patients with mild CARM was conducted with assessments of demographic information, color Doppler echocardiography results, and follow-up data. We performed an analysis of the clinical characteristics of CHD, grouping them based on sex and type of mild CARM.ResultsOf the 183 patients, rectoperineal fistula occurred in 133 patients (72.7%), while the frequency of CHD was 79.8% (146/183). Ventricular septal defects (VSDs) occur more frequently in patients with rectoperineal fistula compared to those with rectovestibular fistula (1.5% vs. 10%), while the opposite trend was observed for patent ductus arteriosus (PDAs) (39.8% vs. 22.0%). Additionally, males presented higher frequency of PDA (42.7% vs. 26.4%) and self-healing (6 months: 87.2% vs. 42.6%; 12 months: 91.0% vs. 63.2%) than females. However, males had a lower rate of undergoing cardiac surgery (6.4% vs. 17.6%) and a younger median diagnosis age (1 day vs. 9 days).ConclusionOur study indicates that there is a necessity for meticulous cardiac assessment and follow-up in neonates diagnosed with mild CARM."

基金机构："National Clinical Research Center for Child Health and Disorders, Children's Hospital of Chongqing Medical University"

基金资助正文：The authors want to thank the nurses and medical officers of Gastrointestinal Neonatal Surgery Department of Children's Hospital affiliated Chongqing Medical University for their support.