Predictive models for starting dose of gonadotropin in controlled ovarian hyperstimulation: review and progress update

作者全名："Guo, Xiaoxiao; Zhan, Hao; Zhang, Xianghui; Pang, Yiwei; Xu, Huishu; Zhang, Baolin; Lao, Kaixue; Ding, Peihui; Wang, Yanlin; Han, Lei"

作者地址："[Guo, Xiaoxiao; Zhang, Xianghui; Pang, Yiwei; Xu, Huishu; Zhang, Baolin; Lao, Kaixue; Ding, Peihui; Wang, Yanlin; Han, Lei] Binzhou Med Univ Hosp, Dept Reprod Med, Binzhou, Shandong, Peoples R China; [Zhan, Hao] Binzhou Med Univ Hosp, Dept Colorectal & Hernial Surg, Binzhou, Shandong, Peoples R China; [Zhang, Baolin] Binzhou Cent Hosp, Dept Obstet & Gynecol, Binzhou, Shandong, Peoples R China; [Han, Lei] Chongqing Med Univ, Affiliated Hosp 3, Dept Obstet & Gynecol, Chongqing, Peoples R China"

通信作者："Wang, YL; Han, L (通讯作者)，Binzhou Med Univ Hosp, Dept Reprod Med, Binzhou, Shandong, Peoples R China."

来源：HUMAN FERTILITY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001150448100010

JCR分区：Q2

影响因子：2.1

年份：2023

卷号：26

期号：6

开始页：1609

结束页：1616

文献类型：Review

关键词：Controlled ovarian hyperstimulation; in vitro fertilization-embryo transfer; starting doses; gonadotropin; predictive model

摘要："Controlled ovarian hyperstimulation (COH) is an essential for in vitro fertilization-embryo transfer (IVF-ET) and an important aspect of assisted reproductive technology (ART). Individual starting doses of gonadotropin (Gn) is a critical decision in the process of COH. It has a crucial impact on the number of retrieved oocytes, the cancelling rate of ART cycles, and complications such as ovarian hyperstimulation syndrome (OHSS), as well as pregnancy outcomes. How to make clinical team more standardized and accurate in determining the starting dose of Gn is an important issue in reproductive medicine. In the past 20 years, research teams worldwide have explored prediction models for Gn starting doses. With the integration of artificial intelligence (AI) and deep learning, it is hoped that there will be more suitable predictive model for Gn starting dose in the future."

基金机构：Natural Science Foundation of Shandong Province

基金资助正文：No Statement Available