Pregnant Patients with Sudden Sensorineural Hearing Loss: Treatments and Efficacy

作者全名："Yang, Sen; Liu, Chonghua; Zhao, Churong; Zuo, Wenqi"

作者地址："[Yang, Sen; Liu, Chonghua; Zhao, Churong] Suining Cent Hosp, Dept Otolaryngol, Suining, Peoples R China; [Zuo, Wenqi] Chongqing Med Univ, Dept Otolaryngol, Affiliated Hosp 1, Chongqing, Peoples R China"

通信作者："Zuo, WQ (通讯作者)，Chongqing Med Univ, Dept Otolaryngol, Affiliated Hosp 1, Chongqing, Peoples R China."

来源：JOURNAL OF INTERNATIONAL ADVANCED OTOLOGY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001156133100005

JCR分区：Q3

影响因子：1

年份：2023

卷号：19

期号：6

开始页：472

结束页：477

文献类型：Article

关键词：Dexamethasone; pregnant; sudden sensorineural hearing loss

摘要："BACKGROUND: The aim of this study was to study the safety and effectiveness of oral and tympanic hormone injection in the treatment of sudden sensorineural hearing loss during pregnancy. METHODS: Data were collected via prospective method. A total of 102 pregnant women with sensorineural hearing loss as experimental group and another 102 patients of sensorineural hearing loss without pregnancy as control group were simultaneously included in the study. Pure tone audiometry test was examined at pre- and posttreatment in 1 week, 2 weeks, and 12 weeks. The experimental group received oral and tympanic hormones, while the control group was treated with the Clinical Practice Guideline: Sudden Hearing Loss (2019) of USA. Recovery rate and hearing gain were assessed by the Clinical Practice Guidelines. RESULTS: After treatment, the effects of the experimental group and the control group were compared at the 1st, 2nd, and 12th week after treatment. It was found that at the 12th week after treatment, the curative effect of the experimental group was significantly different from that of the control group, and the difference was statistically significant. CONCLUSION: The pregnant women with sensorineural hearing loss were more serious than nonpregnant women, and the treatment efficacies were worse than control group. For pregnancy patients with sudden deafness, oral steroids and tympanic cavity injection is an effective, safe first-line treatment option."

基金机构："Science and Health Joint Project, Chongqing, China [2020MSXM107]; Science and Technology Research Program of Chongqing Municipal Education Commission [KJQN201900433]; National Nature Science Foundation of China [81700916]"

基金资助正文："This study was supported by Science and Health Joint Project, Chongqing, China (Grant number: 2020MSXM107), The Science and Technology Research Program of Chongqing Municipal Education Commission (Grant number: KJQN201900433), and The National Nature Science Foundation of China (Grant number: 81700916)."