Value of C-reactive protein/albumin ratio in predicting the development of preoperative oxygenation impairment in patients with Stanford type-B acute aortic dissection

作者全名："Zhao, Xuemin; Bie, Mengjun"

作者地址："[Zhao, Xuemin] Chongqing Med Univ, Affiliated Hosp 1, Branch Hosp 1, Dept Cardiol, Chongqing 400016, Peoples R China; [Bie, Mengjun] Chongqing Med Univ, Affiliated Hosp 1, Dept Cardiothorac Surg, Chongqing 400016, Peoples R China"

通信作者："Bie, MJ (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Dept Cardiothorac Surg, Chongqing 400016, Peoples R China."

来源：IJC HEART & VASCULATURE

ESI学科分类：　

WOS号：WOS:001156744500001

JCR分区：Q2

影响因子：2.5

年份：2024

卷号：50

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：Acute aortic dissection; Oxygenation impairment; C-reactive protein; Albumin

摘要："Objectives: We aimed to assess the predicting value of C-reactive protein (CRP)/albumin ratio (CAR) in the development of Oxygenation impairment (OI) in the patients with Stanford type-B acute aortic dissection (AAD). Methods: This study included 133 patients (age = 58.8 +/- 12.0 years, median age = 61 years, Male/Female = 117/16) diagnosed as Stanford type-B AAD accompanied by hypertension from July 2012 to May 2020. Clinical data were retrospectively extracted from the database. The patients in this study were divided into OI group (oxygenation index <= 200) and non-OI group (oxygenation index > 200). Clinical characteristics in both groups were compared, and predicting value of CAR in the development of OI was assessed. Results: Patients in OI group had higher peak body temperature (37.94 +/- 0.62 vs. 37.67 +/- 0.51 degree celsius, P =.010), higher levels of serum CRP (41.74 +/- 27.71 vs 15.21 +/- 19.66 mg/L, P =.000) and plasma B-type natriuretic peptide (292.14 +/- 251.11 vs 179.80 +/- 241.27 ng/L, P =.016), lower levels of albumin (34.00 +/- 5.14 vs 37.72 +/- 5.24 g/L, P =.000), and higher CAR (1.27 +/- 0.89 vs 0.41 +/- 0.53, P =.000). In multivariate regression analysis, CAR (odds ratio: 5.215, 95 % CI: 2.682; 10.137, P =.000) and the peak body temperature (odds ratio: 2.905, 95 % CI: 1.255; 6.724, P =.013) could significantly predict the OI development. The AUC for CAR was 0.831 (95 % CI: 0.756-0.907). An optimal cutoff value for CAR for predicting OI was >= 0.70, with a sensitivity of 67.5 % and a specificity of 88.2 %. Conclusions: Compared with CRP or albumin alone, the CAR might be a more accurate marker in predicting OI development in Stanford type-B AAD."

基金机构：　

基金资助正文：