"Visual Cognitive Assessment Test: Utility of the brief cognitive battery for early screening of cognitive impairment in Chongqing, China"

作者全名："Liu, Yidan; Xie, Binbin; Li, Qin; Xiao, Shufang; Li, Jiamin; Kandiah, Nagaendran; Ng, Kok Pin; Jiang, Liumi; Li, Xiaofeng"

作者地址："[Liu, Yidan; Xie, Binbin; Li, Qin; Xiao, Shufang; Li, Jiamin; Li, Xiaofeng] Chongqing Med Univ, Affiliated Hosp 2, Dept Neurol, Chongqing, Peoples R China; [Liu, Yidan] Chengdu seventh Peoples Hosp, Dept Neurol, Chengdu, Peoples R China; [Ng, Kok Pin] Natl Neurosci Inst, Dept Neurol, Singapore, Singapore; [Ng, Kok Pin] Duke NUS Med Sch, Singapore, Singapore; [Kandiah, Nagaendran; Ng, Kok Pin] Nanyang Technol Univ Singapore, Lee Kong Chian Sch Med, Singapore, Singapore; [Jiang, Liumi] Ninth Peoples Hosp Chongqing, Dept Neurol, Chongqing, Peoples R China; [Jiang, Liumi] Ninth Peoples Hosp Chongqing, Dept Neurol, 69,Jialing Village, Chongqing 400700, Peoples R China; [Li, Xiaofeng] Chongqing Med Univ, Affiliated Hosp 2, Dept Neurol, 76 Linjiang Rd, Chongqing 400010, Peoples R China"

通信作者："Jiang, LM (通讯作者)，Ninth Peoples Hosp Chongqing, Dept Neurol, 69,Jialing Village, Chongqing 400700, Peoples R China.; Li, XF (通讯作者)，Chongqing Med Univ, Affiliated Hosp 2, Dept Neurol, 76 Linjiang Rd, Chongqing 400010, Peoples R China."

来源：BRAIN AND BEHAVIOR

ESI学科分类：NEUROSCIENCE & BEHAVIOR

WOS号：WOS:001157416100001

JCR分区：Q2

影响因子：2.6

年份：2024

卷号：14

期号：2

开始页：　

结束页：　

文献类型：Article

关键词：cognitive impairment; diagnostic value; screening test; the Visual Cognitive Assessment Test (VCAT); reliability

摘要："Objectives: Early detection of cognitive impairment is essential for timely intervention. Currently, most widely used cognitive screening tests are influenced by language and cultural differences; therefore, there is a need for the development of a language-neutral, visual-based cognitive assessment tool. The Visual Cognitive Assessment Test (VCAT), a 30-point test that assesses memory, executive function, visuospatial function, attention, and language, has demonstrated its utility in a multilingual population. In this study, we evaluated the reliability, validity, and diagnostic performance of the VCAT for screening early cognitive impairment in Chongqing, China Methods: A total of 134 individuals (49 healthy controls (HCs), 52 with mild cognitive impairment (MCI), and 33 with mild dementia) completed the Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), VCAT, and domain-specific neuropsychological assessments. The diagnostic performances of MMSE, MoCA, and VCAT were evaluated using the area under the curve (AUC), sensitivity, and specificity. Construct validity of the VCAT was assessed with well-established domain-specific cognitive assessments. Reliability was measured using Cronbach's alpha. Results: The VCAT and its subdomains demonstrated both good construct validity and internal consistency (alpha = 0.577). The performance of VCAT was comparable to that of MoCA and MMSE in differentiating mild dementia from nondemented groups (AUC: 0.940 vs. 0.902 and 0.977, respectively; p = .098 and .053) and in distinguishing cognitive impairment (CI) from HC (AUC: 0.929 vs. 0.899 and 0.891, respectively; p = .239 and .161), adjusted for education level. The optimal score range for VCAT in determining dementia, MCI, and HC was 0-14, 15-19, and 20-30, respectively. Conclusion: The VCAT proves to be a reliable screening test for early cognitive impairment within our cohort. Being both language and cultural neutral, the VCAT has the potential to be utilized among a wider population within China."

基金机构：Science and technology program projects of the Ninth People's Hospital of Chongqing

基金资助正文："We thank the National Neuroscience Institute, Singapore for giving us the permission to study the Visual Cognitive Assessment Test (VCAT)."