The relationship between ablation range and ablation energy in papillary thyroid microcarcinoma: a comparison between microwave ablation and laser ablation

作者全名："Zhong, Xinyu; Cao, Yuting; Zhang, Xinghao; Liu, Wengang; Zhou, Ping"

作者地址："[Zhong, Xinyu; Zhang, Xinghao; Liu, Wengang; Zhou, Ping] Cent South Univ, Xiangya Hosp 3, Dept Ultrasonog, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China; [Cao, Yuting] Chongqing Med Univ, Affiliated Hosp 2, Inst Ultrasound Imaging, Chongqing 400010, Peoples R China"

通信作者："Zhou, P (通讯作者)，Cent South Univ, Xiangya Hosp 3, Dept Ultrasonog, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China."

来源：EUROPEAN RADIOLOGY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001160030000006

JCR分区：Q1

影响因子：4.7

年份：2024

卷号：　

期号：　

开始页：　

结束页：　

文献类型：Article; Early Access

关键词：Papillary thyroid microcarcinoma; Ultrasonography; Microwaves; Laser therapy; Ablation techniques

摘要："Objectives To study the relationship between the ablation range and applied energy of laser ablation (LA) and microwave ablation (MWA) in papillary thyroid microcarcinoma (PTMC).<br /> Methods A total of 201 PTMC patients were treated with LA (n = 102) or MWA (n = 99) with single-applicator fixed ablation. The ablation range was determined by contrast-enhanced ultrasound. The ratios of ablation volume, longitudinal diameter, and orthogonal diameter to ablation energy (R-AV/E, R-AL/E, R-AO/E) were analyzed and compared between MWA and LA. The effects of PTMC characteristics and Hashimoto's thyroiditis (HT) on ablation efficiency were evaluated by linear regression.<br /> Results The R-AV/E was 0.72 (0.65-0.84) mm(3)/J for MWA and 0.48 (0.39-0.54) mm(3)/J for LA. HT was significantly correlated with R-AV/E of LA (coefficient = - 0.367, p < 0.0001). R-AL/E did not differ significantly between MWA and LA (MWA 0.026 mm/J, LA 0.025 mm/J; p = 0.957). However, MWA had a greater R-AO/E than LA (MWA 0.014 mm/J, LA 0.012 mm/J; p < 0.0001). The plateau values of MWA and LA on the ablation orthogonal diameter were 10.7 mm and 8.69 mm, respectively.<br /> Conclusions MWA showed a higher R-AV/E than LA. More intuitively, MWA had a better ablation performance than LA on the orthogonal axis rather than the longitudinal axis. Theoretically, MWA and LA could achieve complete ablation of <= 6.70 mm and <= 4.69 mm PTMC separately by single-applicator fixed ablation considering a unilateral 2-mm safe margin. HT had a negative effect on LA but not on MWA. Clinical relevance statementThis study establishes strong connections between ablation energy and abla-tion range in papillary thyroid microcarcinoma (PTMC) in vivo, possibly contributing to the supplementation of the PTMC Ablation Consensus or Guidelines and providing a scientific basis for choosing clinical ablation parameters in PTMC."

基金机构：National Natural Science Foundation of China

基金资助正文：No Statement Available