Comparative efficacy of non-invasive brain stimulation for post-stroke cognitive impairment: a network meta-analysis

作者全名："Yan, Mengyu; Liu, Jiarui; Guo, Yiming; Hou, Qingtao; Song, Jiaqi; Wang, Xiaoqin; Yu, Weihua; Lue, Yang"

作者地址："[Yan, Mengyu; Liu, Jiarui; Hou, Qingtao; Wang, Xiaoqin; Lue, Yang] Chongqing Med Univ, Affiliated Hosp 1, Dept Geriatr, 1 Youyi Rd, Chongqing 400016, Peoples R China; [Yan, Mengyu; Guo, Yiming; Song, Jiaqi; Yu, Weihua] Chongqing Med Univ, Inst Neurosci, 1 Yixueyuan St, Chongqing 400016, Peoples R China"

通信作者："Lue, Y (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Dept Geriatr, 1 Youyi Rd, Chongqing 400016, Peoples R China.; Yu, WH (通讯作者)，Chongqing Med Univ, Inst Neurosci, 1 Yixueyuan St, Chongqing 400016, Peoples R China."

来源：AGING CLINICAL AND EXPERIMENTAL RESEARCH

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001160729500003

JCR分区：Q2

影响因子：3.4

年份：2024

卷号：36

期号：1

开始页：　

结束页：　

文献类型：Review

关键词：Non-invasive brain stimulation; Stroke; Cognition; Activities of daily living; Network meta-analysis

摘要："BackgroundNon-invasive brain stimulation (NIBS) is a burgeoning approach with the potential to significantly enhance cognition and functional abilities in individuals who have undergone a stroke. However, the current evidence lacks robust comparisons and rankings of various NIBS methods concerning the specific stimulation sites and parameters used. To address this knowledge gap, this systematic review and meta-analysis seek to offer conclusive evidence on the efficacy and safety of NIBS in treating post-stroke cognitive impairment.MethodsA systematic review of randomized control trials (RCT) was performed using Bayesian network meta-analysis. We searched RCT in the following databases until June 2022: Cochrane Central Register of Controlled Trials (CENTRAL), PUBMED, and EMBASE. We compared any active NIBS to control in terms of improving cognition function and activities of daily living (ADL) capacity following stroke.ResultsAfter reviewing 1577 retrieved citations, a total of 26 RCTs were included. High-frequency (HF)-repetitive transcranial magnetic stimulation (rTMS) (mean difference 2.25 [95% credible interval 0.77, 3.66]) was identified as a recommended approach for alleviating the global severity of cognition. Dual-rTMS (27.61 [25.66, 29.57]) emerged as a favorable technique for enhancing ADL function. In terms of stimulation targets, the dorsolateral prefrontal cortex exhibited a higher ranking in relation to the global severity of cognition.ConclusionsAmong various NIBS techniques, HF-rTMS stands out as the most promising intervention for enhancing cognitive function. Meanwhile, Dual-rTMS is highly recommended for improving ADL capacity."

基金机构：National Key R&D Program of China

基金资助正文：No Statement Available