Efficacy and safety of a panthenol-enriched mask for individuals with distinct impaired skin barrier subtypes

作者全名："Zhang, Xianghua; Tao, Han; Deng, Ya; He, Xiaofeng; Zhang, Zhongxing; Zhong, Liming; Wen, Yue"

作者地址："[Zhang, Xianghua; Tao, Han; He, Xiaofeng; Zhang, Zhongxing; Zhong, Liming; Wen, Yue] Loreal China, Shanghai, Peoples R China; [Deng, Ya] Chongqing Med Univ, Affiliated Hosp 2, Chongqing, Peoples R China"

通信作者："Zhang, XH (通讯作者)，Loreal China, Shanghai, Peoples R China."

来源：JOURNAL OF COSMETIC DERMATOLOGY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001163563600001

JCR分区：Q2

影响因子：2.3

年份：2024

卷号：　

期号：　

开始页：　

结束页：　

文献类型：Article; Early Access

关键词：mask; panthenol; skin barrier

摘要："BackgroundThe protection for different skin types with impaired skin barrier in the market is insufficient.AimTo evaluate the efficacy and safety of a panthenol-enriched mask (La Roche-Posay Mask Pro) in addressing various skin barrier impairment subgroups, including dry sensitive, oily sensitive, and oily acne skin.MethodsA total of 177 participants were enrolled in the study and divided into three subgroups based on their skin type. Participants used the mask following the specified protocol, with measurements taken for skin hydration, transepidermal water loss (TEWL), sebum content, and skin redness-factors that are directly influenced by skin barrier function. Assessments were conducted at baseline and after 1 day (tested 15 min post-application), 7 days, and 14 days of application using Sebumeter, Tewameter, Corneometer, Mexameter, and VISIA.ResultsResults showed significant improvements in skin parameters across all subgroups. In the dry sensitive skin subgroup, the mask increased skin hydration, sebum content, and reduced redness. For the oily sensitive skin subgroup, the mask regulated sebum production and improved skin hydration. In the oily acne skin subgroup, the mask reduced sebum content, redness, TEWL, and post-inflammatory erythema and hyperpigmentation. Tolerance was excellent for all skin types, with no adverse reactions observed.ConclusionsThis study highlights the efficacy and safety of the panthenol-enriched LRP Mask Pro for individuals with distinct skin barrier impairment subgroups. The mask's versatile formulation and proven efficacy make it a valuable skincare product for addressing various skin concerns and achieving healthier, more balanced skin."

基金机构：L'Oreal China

基金资助正文：No Statement Available