"Strong, tough and anisotropic bioinspired hydrogels"

作者全名："Wang, Shu; Lei, Ling; Tian, Yuanhao; Ning, Huiming; Hu, Ning; Wu, Peiyi; Jiang, Hanqing; Zhang, Lidan; Luo, Xiaolin; Liu, Feng; Zou, Rui; Wen, Jie; Wu, Xiaopeng; Xiang, Chenxing; Liu, Jie"

作者地址："[Wang, Shu; Lei, Ling; Ning, Huiming; Hu, Ning; Liu, Feng; Wu, Xiaopeng; Xiang, Chenxing] Chongqing Univ, Coll Aerosp Engn, 174 Shazheng St, Chongqing 400044, Peoples R China; [Wang, Shu] Southwest Univ, Coll Sericulture Text & Biomass Sci, State Key Lab Resource Insects, Chongqing 400715, Peoples R China; [Tian, Yuanhao] Southwest Technol & Engn Res Inst, Chongqing 400039, Peoples R China; [Hu, Ning; Zou, Rui; Wen, Jie] Hebei Univ Technol, Sch Mech Engn, Tianjin 300401, Peoples R China; [Wu, Peiyi] Donghua Univ, Coll Chem Chem Engn & Biotechnol, State Key Lab Modificat Chem Fibers & Polymer Mat, Shanghai 201620, Peoples R China; [Jiang, Hanqing] Westlake Univ, Sch Engn, Hangzhou 310024, Peoples R China; [Zhang, Lidan] Chongqing Med Univ, Sch Basic Med, Chongqing 400042, Peoples R China; [Luo, Xiaolin] Tianjin Univ Tradit Chinese Med, Natl Clin Res Ctr Chinese Med Acupuncture & Moxibu, Teaching Hosp 1, Tianjin 300381, Peoples R China; [Liu, Jie] State Key Lab Adv Design & Mfg Vehicle Body, Changsha 410082, Hunan, Peoples R China"

通信作者："Liu, J (通讯作者)，State Key Lab Adv Design & Mfg Vehicle Body, Changsha 410082, Hunan, Peoples R China."

来源：MATERIALS HORIZONS

ESI学科分类：MATERIALS SCIENCE

WOS号：WOS:001166394900001

JCR分区：Q1

影响因子：12.2

年份：2024

卷号：　

期号：　

开始页：　

结束页：　

文献类型：Article; Early Access

关键词：　

摘要："Soft materials are widely used in tissue engineering, soft robots, wearable electronics, etc. However, it remains a challenge to fabricate soft materials, such as hydrogels, with both high strength and toughness that are comparable to biological tissues. Inspired by the anisotropic structure of biological tissues, a novel solvent-exchange-assisted wet-stretching strategy is proposed to prepare anisotropic polyvinyl alcohol (PVA) hydrogels by tuning the macromolecular chain movement and optimizing the polymer network. The reinforcing and toughening mechanisms are found to be ""macromolecule crystallization and nanofibril formation"". These hydrogels exhibit excellent mechanical properties, such as extremely high fracture stress (12.8 +/- 0.7 MPa) and fracture strain (1719 +/- 77%), excellent modulus (4.51 +/- 0.76 MPa), high work of fracture (134.47 +/- 9.29 MJ m-3), and fracture toughness (305.04 kJ m-2) compared with other strong hydrogels and even natural tendons. In addition, excellent conductivity, strain sensing capability, water retention, freezing resistance, swelling resistance, and biocompatibility can also be achieved. This work provides a new and effective method to fabricate multifunctional anisotropic hydrogels with high tunable strength and toughness with potential applications in the fields of regenerative medicine, flexible sensors, and soft robotics. A novel solvent-exchange-assisted wet-stretching strategy is proposed to prepare anisotropic PVA hydrogels by tuning the macromolecular chain movement and optimizing the polymer network. These hydrogels exhibit excellent mechanical properties."

基金机构："Natural Science Foundation of Chongqing Municipality [12302192, 12227801, 32300666, 52305602]; National Natural Science Foundation of China [2019YFC0840709]; National Key Research and Development Program of China [A2020202002]; Fund for Innovative Research Groups of Natural Science Foundation of Hebei Province [202030507040009]; Key Program of Research and Development of Hebei Province [cstc2021jcyj-msxmX0199, cstc2021jcyj-msxmX0241, cstb2023nscq-msx0303]; Natural Science Foundation of Chongqing [SWU-KQ22025]; Fundamental Research Funds for the Central Universities [KJQN202300222]; Science and Technology Research Program of Chongqing Municipal Education Commission [2022BB004]; Xinjiang Production and Construction Corps Regional Innovation Guidance Program [SJMYF2022X15]; Hebei Province Military-civilian Integration Science and Technology Innovation Project"

基金资助正文："This work was supported by the National Natural Science Foundation of China (Grant No. 12302192, 12227801, 32300666, and 52305602), the National Key Research and Development Program of China (2019YFC0840709), the Fund for Innovative Research Groups of Natural Science Foundation of Hebei Province (A2020202002), the Key Program of Research and Development of Hebei Province (202030507040009), the Natural Science Foundation of Chongqing (cstc2021jcyj-msxmX0199, cstc2021jcyj-msxmX0241, and cstb2023nscq-msx0303), the Fundamental Research Funds for the Central Universities (Grant No. SWU-KQ22025), the Science and Technology Research Program of Chongqing Municipal Education Commission (Grant No. KJQN202300222), the Xinjiang Production and Construction Corps Regional Innovation Guidance Program (2022BB004), and the Hebei Province Military-civilian Integration Science and Technology Innovation Project (SJMYF2022X15). With this acknowledgement, we would like to thank Junchao Huang (Lanzhou University) for his helpful conversations on the creation and modification of the work."