Interconnection of cellular autophagy and endosomal vesicle trafficking and its role in hepatitis B virus replication and release

作者全名："Li, Jia; Lin, Yong; Wang, Xueyu; Lu, Mengji"

作者地址："[Li, Jia; Lu, Mengji] Univ Duisburg Essen, Univ Hosp Essen, Inst Virol, D-45122 Essen, Germany; [Lin, Yong] Chongqing Med Univ, Key Lab Mol Biol Infect Dis, Chinese Minist Educ, Chongqing 400016, Peoples R China; [Wang, Xueyu] Zhejiang Univ, Affiliated Hosp 1, Coll Med, Key Lab Diag & Treatment Infect Dis, Hangzhou 310000, Peoples R China"

通信作者："Lu, MJ (通讯作者)，Univ Duisburg Essen, Univ Hosp Essen, Inst Virol, D-45122 Essen, Germany."

来源：VIROLOGICA SINICA

ESI学科分类：MICROBIOLOGY

WOS号：WOS:001172747100001

JCR分区：Q2

影响因子：4.3

年份：2024

卷号：39

期号：1

开始页：24

结束页：30

文献类型：Review

关键词：Amphisome; Autophagy; Endosomal vesicle; Hepatitis B virus (HBV)

摘要："Hepatitis B virus (HBV) produces and releases various particle types, including complete virions, subviral particles with envelope proteins, and naked capsids. Recent studies demonstrate that HBV exploits distinct intracellular membrane trafficking pathways, including the endosomal vesicle trafficking and autophagy pathway, to assemble and release viral and subviral particles. Herein, we summarize the findings about the distinct roles of autophagy and endosomal membrane trafficking and the interaction of both pathways in HBV replication, assembly, and release."

基金机构：Deutsche Forschungsgemeinschaft [RTG1949/2]; National Natural Science Foundation of China [82202497]

基金资助正文：This work was supported by the Deutsche Forschungsgemeinschaft (RTG1949/2) and the National Natural Science Foundation of China (82202497) .