Comparison of surgical and oncological outcomes between different surgical approaches for overweight or obese cervical cancer patients

作者全名："Chen, Wanli; Wang, Rong; Wu, Jialin; Wu, Yingyu; Xiao, Lin"

作者地址："[Chen, Wanli; Wang, Rong; Wu, Jialin; Wu, Yingyu; Xiao, Lin] Chongqing Med Univ, Dept Gynecol, Affiliated Hosp 1, Chongqing 400016, Peoples R China"

通信作者："Xiao, L (通讯作者)，Chongqing Med Univ, Dept Gynecol, Affiliated Hosp 1, Chongqing 400016, Peoples R China."

来源：JOURNAL OF ROBOTIC SURGERY

ESI学科分类：　

WOS号：WOS:001175455500003

JCR分区：Q2

影响因子：2.2

年份：2024

卷号：18

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Cervical cancer; Radical total hysterectomy; Obesity; Outcomes; Complications

摘要："The purpose was to investigate the safety and advantages of different surgical approaches applied to overweight or obese cervical cancer patients by comparing their surgical and oncological outcomes. This is a retrospective cohort study. 382 patients with a body mass index of at least 24.0 kg/m2 and stage IB-IIA (The International Federation of Gynecology and Obstetrics, FIGO 2009) cervical cancer were enrolled, and then were divided into three groups: open radical hysterectomy (ORH) group, laparoscopic radical hysterectomy (LRH) group, and robot-assisted radical hysterectomy (RRH) group according to the surgical approach. IBM SPSS version 25.0 was used to analyze data. There were 51 patients in ORH group, 225 patients in LRH group and 106 patients in RRH group. In the comparison of surgical outcomes, compared to LRH and ORH, RRH had the shortest operating time, the least estimated blood loss, the shortest postoperative hospital stay, and the shortest recovery time for bowel function (P < 0.05). In the comparison of postoperative complications, ORH has the highest rate of postoperative infection and wound complication compared to LRH and RRH (P < 0.05), and RRH has the highest proportion of urinary retention. After a median follow-up time of 61 months, there was no statistically significant difference between the three groups in terms of 5-year overall survival (OS) rate and 5-year recurrence-free survival (RFS) rate, (P = 0.262, P = 0.453). In patients with overweight or obese cervical cancer, the long-term outcomes of the three surgical approaches were comparable, with RRH showing significant advantages over ORH and LRH in terms of surgical outcomes."

基金机构："Natural Science Foundation of Chongqing, China"

基金资助正文：No Statement Available