Expert Consensus on Ion Channel Drugs for Chronic Pain Treatment in China

作者全名："Ma, Ke; Cheng, Zhixiang; Jiang, Hao; Lin, Zhangya; Liu, Chuansheng; Liu, Xianguo; Lu, Lijuan; Lu, Yan; Tao, Wei; Wang, Suoliang; Yang, Xiaoqiu; Yi, Qishan; Zhang, Xiaomei; Zhang, Ying; Liu, Yanqing"

作者地址："[Ma, Ke; Wang, Suoliang] Shanghai Jiao Tong Univ, Xinhua Hosp, Sch Med, Dept Algol, Shanghai, Peoples R China; [Cheng, Zhixiang] Nanjing Med Univ, Affiliated Hosp 2, Dept Algol, Nanjing, Peoples R China; [Jiang, Hao] Fujian Med Univ, Affiliated Hosp 1, Dept Algol, Fuzhou, Peoples R China; [Lin, Zhangya] Fujian Med Univ, Affiliated Hosp 1, Dept Neurosurg, Fuzhou, Peoples R China; [Liu, Chuansheng] Qingdao Univ, Affiliated Hosp, Dept Algol, Qingdao, Peoples R China; [Liu, Xianguo] Sun Yat Sen Univ, Pain Res Ctr, Zhongshan Sch Med, Guangzhou, Peoples R China; [Lu, Lijuan] Nanjing Univ, Nanjing Drum Tower Hosp, Affiliated Hosp, Dept Pain Med,Med Sch, Nanjing, Peoples R China; [Lu, Yan] Fourth Mil Med Univ, Xijing Hosp, Dept Algol, Xian, Peoples R China; [Tao, Wei] Shenzhen Univ, Gen Hosp, Dept Neurosurg, Shenzhen, Peoples R China; [Wang, Suoliang] Xi An Jiao Tong Univ, Affiliated Hosp 1, Dept Algol, Xian, Peoples R China; [Yang, Xiaoqiu] Chongqing Med Univ, Affiliated Hosp 1, Dept Algol, Chongqing, Peoples R China; [Yi, Qishan] Chongqing Med Univ, Yibin Peoples Hosp Affiliated 1, Dept Algol, Yibin, Peoples R China; [Zhang, Xiaomei] Kunming Med Univ, Affiliated Hosp 1, Dept Algol, Kunming, Peoples R China; [Zhang, Ying] Southwest Med Univ, Hosp TCM, Dept Algol, Luzhou, Peoples R China; [Liu, Yanqing] Capital Med Univ, Beijing Tiantan Hosp, Dept Algol, Beijing, Peoples R China; [Ma, Ke] Shanghai Jiao Tong Univ, Xinhua Hosp, Sch Med, Dept Algol, Shanghai 200092, Peoples R China; [Liu, Yanqing] Capital Med Univ, Beijing Tiantan Hosp, Dept Algol, Beijing 100070, Peoples R China"

通信作者："Ma, K (通讯作者)，Shanghai Jiao Tong Univ, Xinhua Hosp, Sch Med, Dept Algol, Shanghai 200092, Peoples R China.; Liu, YQ (通讯作者)，Capital Med Univ, Beijing Tiantan Hosp, Dept Algol, Beijing 100070, Peoples R China."

来源：JOURNAL OF PAIN RESEARCH

ESI学科分类：NEUROSCIENCE & BEHAVIOR

WOS号：WOS:001182068200001

JCR分区：Q2

影响因子：2.5

年份：2024

卷号：17

期号：　

开始页：953

结束页：963

文献类型：Review

关键词：chronic pain; ion channel drugs; voltage -gated calcium channels; voltage -gated sodium channel

摘要："Ion channel drugs have been increasing used for chronic pain management with progress in the development of selective calcium channel modulators. Although ion channel drugs have been proven safe and effective in clinical practice, uncertainty remains regarding its use to treat chronic pain. To standardize the clinical practice of ion channel drug for the treatment of chronic pain, the National Health Commission Capacity Building and Continuing Education Center for Pain Diagnosis and Treatment Special Ability Training Project established an expert group to form an expert consensus on the use of ion channel drugs for the treatment of chronic pain after repeated discussions on existing medical evidence combined with the well clinical experience of experts. The consensus provided information on the mechanism of action of ion channel drugs and their recommendations, caution use, contraindications, and precautions for their use in special populations to support doctors in their clinical decision-making."

基金机构：National Natural Science Foundation of China (peripheral mechanism of Mrgprd regulating opioid tolerance by a specific lncRNA in the dorsal root ganglion) [NSFC-82371224]

基金资助正文：This work was supported by National Natural Science Foundation of China (peripheral mechanism of Mrgprd regulating opioid tolerance by a specific lncRNA in the dorsal root ganglion) (NSFC-82371224) .