Thermophoretic Assay for Biosensing

作者全名："Ling, Haixiang; Yuan, Yunhe; Chen, Fuli; Guo, Jiuchuan; Guo, Jinhong; Li, Diangeng"

作者地址："[Ling, Haixiang; Guo, Jinhong] Shanghai Jiao Tong Univ, Sch Sensing Sci & Engn, Shanghai 200240, Peoples R China; [Yuan, Yunhe] Chongqing Med Univ, Coll Lab Med, MOE Key Lab Lab Med Diagnost, 1 Yixueyuan Rd, Chongqing 400016, Peoples R China; [Chen, Fuli] Harbin Inst Technol Shenzhen, Sch Mat Sci & Engn, Sauvage Lab Smart Mat, Shenzhen 518055, Peoples R China; [Guo, Jiuchuan] Univ Elect Sci & Technol China, Sch Informat & Commun Engn, Chengdu 611731, Peoples R China; [Li, Diangeng] Capital Med Univ, Beijing Chaoyang Hosp, Dept Sci Res, 8 Gongti South Rd, Beijing 100020, Peoples R China"

通信作者："Guo, JH (通讯作者)，Shanghai Jiao Tong Univ, Sch Sensing Sci & Engn, Shanghai 200240, Peoples R China.; Guo, JC (通讯作者)，Univ Elect Sci & Technol China, Sch Informat & Commun Engn, Chengdu 611731, Peoples R China.; Li, DG (通讯作者)，Capital Med Univ, Beijing Chaoyang Hosp, Dept Sci Res, 8 Gongti South Rd, Beijing 100020, Peoples R China."

来源：ADVANCED MATERIALS TECHNOLOGIES

ESI学科分类：MATERIALS SCIENCE

WOS号：WOS:001193568600001

JCR分区：Q1

影响因子：6.4

年份：2024

卷号：　

期号：　

开始页：　

结束页：　

文献类型：Review; Early Access

关键词：biosensors; in vitro diagnosis; thermophoresis

摘要："Thermophoresis refers to the directional movement of particles driven by temperature gradients, which is ubiquitous in nature. This phenomenon can be conveniently used to manipulate molecules and objects such as biomolecules, colloids, metal nanoparticles, and cells. Because of these advantages, thermophoresis is widely used in biosensing. In vitro diagnosis, as an important field of biosensing, is highly compatible with thermophoresis. Compared with traditional in vitro diagnostic techniques, thermophoretic diagnosis is a homogeneous system that boasts high efficiency and rapid detection as well as a wide detection range; thus, thermophoresis has a myriad of applications. The emergence of microscale and multifield coupling thermophoresis technologies yield widespread applications of thermophoresis in the field of in vitro diagnostics. This study presents the history of thermophoresis and reviews various cases of biosensors utilizing thermophoresis. Those biosensors are widely used in in vitro diagnostics, biomarker discovery, and other fields. Furthermore, it assesses the advantages of thermophoresis, and finally discusses its current challenges and future development. This article summarizes the use of thermophoresis in biosensing - with a focus on in vitro diagnosis. It also analyzes various case studies of the use of thermophoresis in vitro diagnosis and compares the advantages and disadvantages of thermophoresis with other techniques. Finally, the article gives an outlook on the future of thermophoresis. image"

基金机构：National Natural Science Foundation of China; [62122017]

基金资助正文：This work was supported by National Natural Science Foundation of China (Grant: 62122017).