The effects of initial and subsequent overweight or obesity on hypertension in the middle age

作者全名："Pan, Pei; Yang, Ying; He, Sen; Zhao, Gang; Chen, Xiao-Ping"

作者地址："[Pan, Pei; Yang, Ying; Zhao, Gang] Chongqing Med Univ, Univ Town Hosp, Dept Cardiovasc, Chongqing, Peoples R China; [He, Sen; Chen, Xiao-Ping] Sichuan Univ, West China Hosp, Dept Cardiovasc, 37GuoXue Rd WuHou Dist, Chengdu 610041, Sichuan, Peoples R China"

通信作者："Chen, XP (通讯作者)，Sichuan Univ, West China Hosp, Dept Cardiovasc, 37GuoXue Rd WuHou Dist, Chengdu 610041, Sichuan, Peoples R China."

来源：JOURNAL OF CLINICAL HYPERTENSION

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001193855800001

JCR分区：Q2

影响因子：2.7

年份：2024

卷号：　

期号：　

开始页：　

结束页：　

文献类型：Article; Early Access

关键词：adiposity status; BMI; cardiovascular disease; hypertension; middle-age

摘要："The aims of our study were to examine whether initial or subsequent adiposity status had a greater effect on hypertension. We collected data in 1992 and again in 2007 from the same group of 597 individuals in the middle age. The subjects were classified into four groups: individuals with a normal body mass index (BMI) in 1992 and 2007 were in Group I; those with a normal BMI in 1992, but became overweight or obese in 2007 were in Group II; those who were overweight or obese in 1992, but had a normal BMI in 2007 were in Group III; and those who were overweight or obese in 1992 and 2007 were in Group IV. Their demographic data were recorded. The relationship between adiposity status and hypertension was analyzed using logistic regression model. The cumulative incidence of hypertension was 35.5%, 56.3%, 50.0%, and 65.1% for Group I to IV, respectively. Compared with Group I, after adjusted factors, the hazard ratio (HR) was 1.80 for Group II (P = .001), 1.40 for Group III (P = .150), and 2.31 for Group IV (P < .001). Adiposity status in 2007 could predict hypertension (OR = 2.5, P < .001), as opposed to the initial adiposity status (P = .148). Subsequently adiposity status could have major effects on hypertension. Our society is very short of public health resources, particularly in developing countries, we should pay more attention to current adiposity status and encourage middle-aged people to lose weight."

基金机构："the National Eighth Five-Year Research Plan, China [85-915-01-02]; National Eighth Five-Year Research Plan, China [2006BAI01A01]; Mega-projects of Science Research for the 11th Five-Year Plan, China"

基金资助正文："This study is supported by the National Eighth Five-Year Research Plan, China (grant no: 85-915-01-02); Mega-projects of Science Research for the 11th Five-Year Plan, China (grant no: 2006BAI01A01)."