Comparing surgical site wound infection after laparoscopic and open radical cystectomies in patients with bladder cancer

作者全名："Luo, Hua-Ming; Xiong, Yong-Jiang"

作者地址："[Luo, Hua-Ming; Xiong, Yong-Jiang] Chongqing Med Univ, Yongchuan Hosp, Dept Urol, Chongqing, Peoples R China; [Xiong, Yong-Jiang] Chongqing Med Univ, Yongchuan Hosp, Dept Urol, Chongqing 402160, Peoples R China"

通信作者："Xiong, YJ (通讯作者)，Chongqing Med Univ, Yongchuan Hosp, Dept Urol, Chongqing 402160, Peoples R China."

来源：INTERNATIONAL WOUND JOURNAL

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001196300500001

JCR分区：Q1

影响因子：2.6

年份：2024

卷号：21

期号：4

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结束页：　

文献类型：Article

关键词：bladder cancer; complications; laparoscopic radical cystectomy; wound infections

摘要："This study comprehensively compared the effects of laparoscopic and open radical cystectomies on postoperative wound infections and complications in patients with bladder cancer. We conducted a systematic search for relevant studies in PubMed, Embase, Google Scholar, Cochrane Library, China National Knowledge Infrastructure, and Wanfang databases, from database inception to October 2023. Two researchers independently screened the literature, extracted data, and assessed the quality based on the inclusion and exclusion criteria. Data analysis was performed using Stata 17.0 software. Overall, 16 studies involving 1427 patients with bladder cancer were included. The analysis revealed that, compared with open radical cystectomy, laparoscopic radical cystectomy significantly reduced the incidence of wound infections (odds ratio [OR] = 0.38, 95% confidence interval [CI]: 0.23-0.64, p < 0.001) and complications (OR = 0.35, 95%CI: 0.26-0.47, p < 0.001) and significantly shortened the hospital stay duration (standardised mean difference [SMD] = -1.85, 95%CI: -2.34 to -1.36, p < 0.001). Thus, this study determined that laparoscopic radical cystectomy for the treatment of bladder cancer effectively reduced the occurrence of wound infections and complications, and significantly shortened the patient's hospital stay, demonstrating notable therapeutic effectiveness worthy of clinical application."

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