Effects of task-based mirror therapy on upper limb motor function in hemiplegia: study protocol for a randomized controlled clinical trial

作者全名：Liu, Hongzhen; Xu, Yangjie; Jiang, Wei; Hu, Fangchao; Zhou, Yi; Pan, Lu; Zhou, Feng; Yin, Ying; Tan, Botao

作者地址：[Liu, Hongzhen; Xu, Yangjie; Jiang, Wei; Zhou, Yi; Pan, Lu; Zhou, Feng; Yin, Ying; Tan, Botao] Chongqing Med Univ, Affiliated Hosp 2, Dept Rehabil Med, 74 Lin Jiang Rd, Chongqing 40010, Peoples R China; [Hu, Fangchao] Chongqing Univ Technol, Dept Mech Engn, 69 Hongguang Ave, Chongqing 400054, Peoples R China

通信作者：Tan, BT (通讯作者)，Chongqing Med Univ, Affiliated Hosp 2, Dept Rehabil Med, 74 Lin Jiang Rd, Chongqing 40010, Peoples R China.

来源：TRIALS

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001200758600002

JCR分区：Q3

影响因子：2

年份：2024

卷号：25

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Task-based mirror therapy; Stroke; Hand function rehabilitation; Diffusion tensor imaging

摘要：Background and purpose Research to date has lacked definitive evidence to determine whether mirror therapy promotes the recovery of upper extremity function after stroke. Considering that previous studies did not stratify patients based on structural retention, this may be one of the reasons for the negative results obtained in many trials. The goal evaluates the efficacy of TBMT (utilizing an innovatively designed mirror) versus standard occupational therapy for stroke patient's upper limb functionality.Methods and analysis This single-center randomized controlled trial will involve 50 patients with stroke. All patients will be randomly assigned to either the task-based mirror therapy or the control group. The interventions will be performed 5 days per week for 4 weeks. The primary outcomes will be the mean change in scores on both the FMA-UE and modified Barthel Index (MBI) from baseline to 4 weeks intervention and at 12 weeks follow-up between the two groups and within groups. The other outcomes will include the Action Research Arm Test (ARAT), the Nine Hole Peg Test (9HPT), the Functional Independence Measure, and MRI.Discussion This trial will not only to establish that task-based mirror therapy (TBMT) could improve the recovery of hand function after stroke but also to explore the underlying mechanisms. We expect that this finding will clarify the brain activation and brain network mechanisms underlying the improvement of hand function with task-oriented mirror therapy and lead to new ideas for stroke hand function rehabilitation.Trial registration URL: https://www.chictr.org.cn; Unique identifier: ChiCTR2300068855. Registered on March 1, 2023

基金机构：Kuanren Talents Program of the Second Affiliated Hospital of Chongqing Medical University; Chongqing Medical Scientific Research Project (Joint Project of Chongqing Health Commission and Science and Technology Bureau) [2023MSXM037]

基金资助正文：Both BTT, YY, and WJ have acquired the rewards of the Kuanren Talents Program of the Second Affiliated Hospital of Chongqing Medical University. This work is supported by the Chongqing Medical Scientific Research Project (Joint Project of Chongqing Health Commission and Science and Technology Bureau), No. 2023MSXM037. The funders had no role in the study design, data collection, or analysis of the manuscript.