Toxicological Research on Nano and Microplastics in Environmental Pollution: Current Advances and Future Directions

作者全名：Shukla, Saurabh; Pei, Yang; Li, Wei-Guo; Pei, De-Sheng

作者地址：[Shukla, Saurabh; Pei, De-Sheng] Chongqing Med Univ, Sch Publ Hlth, Chongqing 400016, Peoples R China; [Shukla, Saurabh; Li, Wei-Guo] Henan Normal Univ, Coll Life Sci, Xinxiang 453007, Henan, Peoples R China; [Pei, Yang] Chongqing 11 Middle Sch, Chongqing 400061, Peoples R China; [Shukla, Saurabh] Lovely Profess Univ, Sch Bioengn & Biosci, Dept Forens Sci, Jalandhar, India

通信作者：Pei, DS (通讯作者)，Chongqing Med Univ, Sch Publ Hlth, Chongqing 400016, Peoples R China.

来源：AQUATIC TOXICOLOGY

ESI学科分类：PLANT & ANIMAL SCIENCE

WOS号：WOS:001208504900001

JCR分区：Q1

影响因子：4.1

年份：2024

卷号：270

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：Nanoplastics; Microplastics; Toxicity; Pollution; Health risk

摘要：This review explains the sources of nanoplastics (NPs) and microplastics (MPs), their release, fate, and associated health risks in the aquatic environment. In the 21st century, scientists are grappling with a major challenge posed by MPs and NPs. The global production of plastic has skyrocketed from 1.5 million tons in the 1950s to an astonishing 390.7 million tons in 2021. This pervasive presence of these materials in our environment has spurred scientific inquiry into their potentially harmful effects on living organisms. Studies have revealed that while MPs, with their larger surface area, are capable of absorbing contaminants and pathogens from the surroundings, NPs can easily be transferred through the food chain. As a result, living organisms may ingest them and accumulate them within their bodies. Due to their minuscule size, NPs are particularly difficult to isolate and quantify. Furthermore, exposure to both NPs and MPs has been linked to various adverse health effects in aquatic species, including neurological impairments, disruption of lipid and energy metabolism, and increased susceptibility to cytotoxicity, oxidative stress, inflammation, and reactive oxygen species (ROS) production. It is alarming to note that MPs have even been detected in commercial fish, highlighting the severity of this issue. There are also challenges associated with elucidating the toxicological effects of NPs and MPs, which are discussed in detail in this review. In conclusion, plastic pollution is a pressing issue that governments should tackle by ensuring proper implementation of rules and regulations at national and provincial levels to reduce its health risks.

基金机构：Chongqing Medical University [R4014]; Chongqing Postdoctoral Innovation Mentor Studio; Postdoctoral Scholarship Program of Henan Normal University; [X7928 D]

基金资助正文：The authors are thankful for the Chongqing Medical University (R4014) , Chongqing Postdoctoral Innovation Mentor Studio (X7928 D. S.P.) , Postdoctoral Scholarship Program of Henan Normal University (to S.S) , Program of China-Sri Lanka Joint Research and Demonstration Center for Water Technology, and China-Sri Lanka Joint Center for Education and Research by Chinese Academy of Sciences, China.