Hybrid functional membranes through layer-by-layer assembly of Ti₃C₂T_x MXene and gelatin-stabilized calcium phosphate nanospheres

作者全名：Rezvan, Gelareh; Gholamirad, Farivash; Walden, Mary K.; Wang, Yonghui; Zhao, Piao; Sadati, Monirosadat; He, Tong-Chuan; Taheri-Qazvini, Nader

作者地址：[Rezvan, Gelareh; Gholamirad, Farivash; Sadati, Monirosadat; Taheri-Qazvini, Nader] Univ South Carolina, Dept Chem Engn, Columbia, SC 29208 USA; [Walden, Mary K.; Taheri-Qazvini, Nader] Univ South Carolina, Dept Biomed Engn, Columbia, SC 29208 USA; [Wang, Yonghui; Zhao, Piao; He, Tong-Chuan] Univ Chicago, Med Ctr, Dept Orthopaed Surg & Rehabil Med, Mol Oncol Lab, Chicago, IL 60637 USA; [Wang, Yonghui] Shanghai Jiao Tong Univ, Sch Med, Dept Endocrinol, Shanghai 200000, Peoples R China; [Zhao, Piao] Chongqing Med Univ, Affiliated Hosp 1, Dept Orthopaed Surg, Chongqing 400016, Peoples R China

通信作者：Taheri-Qazvini, N (通讯作者)，Univ South Carolina, Dept Chem Engn, Columbia, SC 29208 USA.; Taheri-Qazvini, N (通讯作者)，Univ South Carolina, Dept Biomed Engn, Columbia, SC 29208 USA.

来源：APPLIED MATERIALS TODAY

ESI学科分类：MATERIALS SCIENCE

WOS号：WOS:001209253900001

JCR分区：Q1

影响因子：7.2

年份：2024

卷号：37

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：MXene; Layer-by-layer assembly; Amorphous calcium phosphate; Hybrid membrane; Good stability

摘要：MXene-based membranes exhibit promising properties for various applications; however, pure MXene membranes lack sufficient environmental stability and mechanical strength. This work demonstrates that incorporating gelatin-stabilized amorphous calcium phosphate (Gel-ACP) nanospheres into MXene membranes via layerby-layer assembly significantly enhances flexibility and mechanical strength while retaining electrical conductivity. A pressure-assisted stacking technique was introduced to efficiently fabricate membranes with tunable thickness not achievable through single filtration steps. The Gel-ACP nanospheres, synthesized by coprecipitation of calcium phosphate within gelatin solution, provided a ductile and cytocompatible reinforcement that augmented the properties of the MXene matrix. Direct mixing of the components led to particle aggregation and non-uniform dispersion. In contrast, controlled layer-by-layer nanostructuring maintained membrane conductivity around 10(2) Scm(-1) while dramatically improving mechanical integrity. The optimized hybrid membranes exhibited specific electromagnetic shielding effectiveness of similar to 21,000 dBcm(2)g(-1) and withstood over 90 kPa vacuum pressure without rupture, six times higher than pure MXene membranes. Cytocompatibility was confirmed by the proliferation of human mesenchymal stem cells on the membranes. Moreover, the layered membrane exhibited excellent adhesion to bone-mimicking structures, indicating potential utility for bone tissue engineering. Overall, this work provides new design principles for engineering hybrid membranes through controlled multicomponent assembly to overcome intrinsic limitations and impart multifunctionality.

基金机构：National Science Foundation, USA [2238908]

基金资助正文：This research was supported by funding from the National Science Foundation, USA (award #2238908) . We appreciate Prof. G. Wang from the Electrical Engineering Department at the University of South Car- olina for providing access to the vector network analyzer.