Body Mass Index and All-Cause Mortality in Elderly Patients with Percutaneous Coronary Intervention: A Meta-Analysis

作者全名：Wang, Yunhui; Li, Junwu; Zhang, Yulian; Chen, Shiyu; Zheng, Fang; Deng, Wei

作者地址：[Wang, Yunhui] Chongqing Med Univ, Bishan Hosp Chongqing, Bishan Hosp, Dept Nephrol, Chongqing, Peoples R China; [Li, Junwu] Chongqing Med Univ, Affiliated Hosp 1, Dept Urol, Chongqing, Peoples R China; [Zhang, Yulian] Chongqing Med Univ, Banan Hosp, Dept Gen Med, Chongqing, Peoples R China; [Zheng, Fang] Chongqing Med Univ, Affiliated Hosp 2, Dept Geriatr, Chongqing, Peoples R China; [Chen, Shiyu; Deng, Wei] Chongqing Med Univ, Affiliated Hosp 2, Dept Gen Med, Chongqing, Peoples R China

通信作者：Deng, W (通讯作者)，Chongqing Med Univ, Affiliated Hosp 2, Dept Gen Med, Chongqing, Peoples R China.

来源：OBESITY FACTS

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001216728600001

JCR分区：Q2

影响因子：3.9

年份：2024

卷号：17

期号：3

开始页：227

结束页：236

文献类型：Article

关键词：Percutaneous coronary intervention; Obesity; Body mass index; Elderly patients; Meta-analysis

摘要：Introduction: The "obesity paradox" in elderly patients suffering from percutaneous coronary intervention (PCI) remains a source of controversy. The present meta-analysis focused on exploring the real existence of "obesity paradox" in these patients. Methods: As of November 2022, PubMed, Cochrane, and Embase databases were comprehensively searched to identify articles reporting all-cause mortality according to diverse body mass index (BMI) categories after PCI among the old cases developing coronary artery disease (CAD). Summary estimates of relative risks (RRs) were assigned to four BMI groups, including underweight, normal weight, overweight, and obesity groups. Results: There were altogether nine articles involving 25,798 cases selected for further analysis. Relative to normal weight group, overweight and obesity groups had decreased all-cause mortality (RR: 0.86, 95% CI: 0.77-0.95 for overweight group; RR: 0.57, 95% CI: 0.40-0.80 for obesity group), while underweight group had elevated all-cause mortality (RR: 1.52, 95% CI: 1.01-2.29). Conclusion: Our study revealed an "obesity paradox" relation of BMI with all-cause mortality in elderly cases receiving PCI. In comparison with normal weight group, overweight and obesity groups had decreased all-cause mortality, while underweight group had increased all-cause mortality.

基金机构：Key Project of Health of Chongqing Science and Technology Bureau [CSTC2021jscx-gksb-N0016]; Kuanren Talent Program of the Second Affiliated Hospital of Chongqing Medical University [KRYC-GG-2113]; Project of Chongqing Sports Bureau [C202005]; Chongqing Joint Scientific Research Project of Science and Technology [2021MSXM094]

基金资助正文：The present study was financially supported by the Key Project of Health of Chongqing Science and Technology Bureau (No. CSTC2021jscx-gksb-N0016), the Kuanren Talent Program of the Second Affiliated Hospital of Chongqing Medical University (No. KRYC-GG-2113), the Project of Chongqing Sports Bureau (No. C202005), and the Chongqing Joint Scientific Research Project of Science and Technology (No. 2021MSXM094). All funders were not involved in designing the study, collecting or analyzing data, making decision on publication, and preparing this manuscript.