Case report: Primary myelofibrosis presenting with portal hypertension mimicking cirrhosis

作者全名：Gan, Xiayu; Yu, Shengjie; Zhu, Min; Ning, Bo; He, Song; Xie, Xiaoyue; Tu, Linshuang; Yu, Huihong

作者地址：[Gan, Xiayu; Ning, Bo; He, Song; Xie, Xiaoyue; Tu, Linshuang; Yu, Huihong] Chongqing Med Univ, Affiliated Hosp 2, Dept Gastroenterol, Chongqing, Peoples R China; [Yu, Shengjie] Chongqing Med Univ, Affiliated Hosp 2, Dept Urol, Chongqing, Peoples R China; [Zhu, Min] First Peoples Hosp Neijiang, Dept Geriatr, Neijiang, Peoples R China

通信作者：Yu, HH (通讯作者)，Chongqing Med Univ, Affiliated Hosp 2, Dept Gastroenterol, Chongqing, Peoples R China.

来源：FRONTIERS IN MEDICINE

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001224198100001

JCR分区：Q1

影响因子：3.1

年份：2024

卷号：11

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：primary myelofibrosis; portal hypertension; cirrhosis; liver biopsy; treatment

摘要：Primary myelofibrosis (PMF) is an infrequent etiology of noncirrhotic portal hypertension (PH). In clinical settings, non-cirrhotic PH is often misdiagnosed as cirrhotic PH. This case report details a patient who exhibited recurrent esophageal variceal hemorrhage and was initially misdiagnosed with cirrhosis. Initially poised for liver transplantation, the patient's liver biopsy revealed no significant cirrhosis but showed signs of extramedullary hematopoiesis (EMH). Following the accurate diagnosis of PMF, the patient underwent standard treatment, leading to an absence of recurrent gastrointestinal hemorrhage due to esophageal varices for nearly three years.

基金机构：Senior Medical Talents Program of Chongqing for Young and Middle-aged individuals

基金资助正文：The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. The Senior Medical Talents Program of Chongqing for Young and Middle-aged individuals.